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Characterizing Three Heat Shock Protein 70 Genes of and Their Expression in Response to Temperature and Insecticide Stress.

J Agric Food Chem

January 2025

State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

is a highly polyphagous pest that causes substantial agricultural damage. Temperature and insecticides are two major abiotic stresses affecting their population abundance. Heat shock proteins play an essential role in cell protection when insects are exposed to environmental stresses.

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Smartphone-based non-invasive detection of salivary uric acid based on the fluorescence quenching of gleditsia sinensis carbon dots.

Mikrochim Acta

January 2025

Guizhou Province, Qianzhi Mingguang Soaphorn Rice Processing Base, Zhijin County, Maochang Town, Bijie CityBijie City, 552103, China.

A smartphone-based non-invasive method was developed for salivary uric acid detection using Gleditsia Sinensis carbon dots (GS-CDs). The GS-CDs synthesized by the one-pot hydrothermal method emitted blue fluorescence at a maximum excitation wavelength of 350 nm and had good fluorescence stability in the presence of different ions, while showing selectivity to uric acid solution. The ability of uric acid (UA) to quench the fluorescent substances present in the GS-CDs, was confirmed through HPLC-FLD and LC-MS, FTIR and XPS.

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Methotrexate (MTX) is an antimetabolite drug utilized for managing a variety of cancers and autoinflammatory conditions. MTX may trigger detrimental effects in mout, h tissues, including salivary gland impairment. Bosentan (BOS), a drug that blocks endothelin receptors, has strengthened antioxidant, anti-inflammatory, and anti-apoptotic properties.

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Background: Radiotherapy is one of the main treatments for head and neck cancer; however, due to its non-selectivity the glandular tissue can be affected. This scoping review aimed to identify the evidence about mesenchymal stem cell therapies for irradiated salivary gland regeneration.

Material And Methods: Two independent reviewers performed a literature search in MEDLINE/PubMed, Scopus, and Web of Science.

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Tick salivary cystatin Iristatin limits the virus replication in skin of tick-borne encephalitis virus-infected mice.

Parasitol Res

January 2025

Department of Medical Biology, Faculty of Science, University of South Bohemia, Branišovská 1760, CZ-37005, České Budějovice, Czech Republic.

Tick-borne encephalitis virus (TBEV) is flavivirus transmitted to the host via tick saliva which contains various molecules with biological impacts. One of such molecules is Iristatin, a cysteine protease inhibitor from Ixodes ricinus that has been shown to have immunomodulatory properties. To characterize Iristatin in the relation to TBEV, we investigate whether this tick inhibitor has any capacity to influence TBEV infection.

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