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In vitro cytotoxicity (irritant potency) of toothpaste ingredients.
PLoS One
January 2025
Department of Dental Materials Science, Academic Center for Dentistry (ACTA), University of Amsterdam, Amsterdam, The Netherlands.
Purpose: This study aimed to determine the cytotoxicity (irritant potency) of toothpaste ingredients, of which some had known to have sensitizing properties.
Materials: From the wide variety of toothpaste ingredients, Xylitol, Propylene glycol (PEG), Sodium metaphosphate (SMP), Lemon, Peppermint, Fluoride, Cinnamon, and Triclosan and Sodium dodecyl sulphate (SDS) have been selected for evaluation of their cytotoxic properties.
Methods: Reconstructed human gingiva (RHG) were topically exposed to toothpaste ingredients at different concentrations.
Effects of Hyaluronic Acid on Three Different Cell Types of the Periodontium in a Novel Multi-Culture Cell Plate: An Exploratory Study.
Biomolecules
January 2025
Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands.
Hyaluronic acid (HA) has received considerable attention in the reconstruction of lost periodontal tissues. HA has been proposed to play a role in cell proliferation, differentiation, migration, and cell-matrix as well as cell-cell interactions. Although various studies have been conducted, further research is needed to expand our knowledge based on HA such as its effects on cell proliferation and osteogenic differentiation.
View Article and Find Full Text PDF[Analysis of soft tissue healing after keratinized tissue augmentation in reconstructed jaws].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2025
Department of Periodontology, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.
Objective: To evaluate the wound healing of recipient and donor sites following keratinized mucosa augmentation (KMA) around implants in reconstructed jaw areas and to compare these outcomes with gingival grafts in native jawbone, so as to provide clinical guidance for postoperative maintenance, and to investigate the impact of clinical experience on the evaluation of KMA postoperative healing through subgroup comparisons.
Methods: This study included patients who underwent resection of maxillofacial tumors, fibular or iliac flap reconstruction, and implant placement at Peking University Dental Hospital from October 2020 to April 2023. Three months post-implant placement, the patients were referred for KMA procedures.
Mandibular hybrid odontogenic tumor.
Oral Maxillofac Surg
January 2025
Department of Dentistry, State University of Maringá (UEM), Maringá, Brazil.
Background: Hybrid Odontogenic Tumors (HOT) are defined by the presence of two or more independent odontogenic tumors that originate from and affect the same maxillofacial site.
Methods: The present study is the first case report of a mandibular HOT consisting of Ameloblastoma, Calcifying Epithelial Odontogenic Tumor, and Ameloblastic Fibroma.
Case Report: A 37-year-old otherwise healthy male presented with the chief complaint of swelling in the right mandibular body.
Modified titanium post with polished sidewalls and prefabricated shoulders can effectively preserve the teeth with subgingival defects.
Sci Rep
January 2025
Jinzhou Medical University School of Stomatology, Liaoning, People's Republic of China.
Objective of this study was to examine the clinical efficacy and mechanical characteristics of the modified titanium post in the restoration of subgingival defect teeth. Teeth with subgingival defects depth ≥ 2 mm were randomly restored using a fiber post after crown lengthening and a modified titanium post, respectively. Gingival index, sulcus bleeding index, probing depth, tooth mobility, and gingival papilla height were recorded before and after restoration.
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