The most common causes of mycogenic allergies of the respiratory tract are cladosporium-, aspergillus-, ustilago-, monilia- and alternaria-species. On the second place follow species of epicoccum and penicillium as well a some asco- and basidiomycetes. The majority of these germs represents banal molds whose natural habitat is predominantly the soil and the vegetable kingdom. Under the circumstances of civilisation, however, they may occur in the immediate human environment in enormous amounts (more than 10.000 spores/m3 of air). There are great differences in the quantity and distribution of the single germs with regard to the geographic, seasonal and economic situation. A survey of these aspects is given.
Download full-text PDF |
Source |
---|
Aim: To study of therapeutic activity of local (natamycine) and systemic (fluconasol) antifungal drugs in patients with atopic dermatitis (AD) with mycogenic sensitization and candida carriage.
Materials And Methods: 29 patients with severe AD and diagnosed contamination of the skin lesions with yeast fungi have received antifungal treatment with fungicidal drugs in low-dose long-term course.
Results: The drugs were effective in 83% of patients: poor effect was in 28%, moderate--in 21% and good--in 34% of cases.
Zh Mikrobiol Epidemiol Immunobiol
June 1998
Medical Academy of Post-Diploma Education, St. Petersburg, Russia.
The method of genetic selection has been used for obtaining the fungal cultures of Aspergillus strains, producers of allergen-active substances. The natural variability of populations of A. fumigatus, A.
View Article and Find Full Text PDFZh Mikrobiol Epidemiol Immunobiol
September 1990
In the dynamic survey of 577 persons having had contacts with yeast-like fungi of the genus Candida the effectiveness of tests for the diagnosis of mycogenic sensitization was made with the use of a number of immunological methods. The basophil degranulation test was shown to have higher sensitivity and specificity in the detection of hypersensitivity to microbial strains used in the production processes of microbiological synthesis, while the use of polysaccharide antigens is more expedient in immunological reactions, such as the precipitation test with the finished product obtained by these processes and with C. albicans.
View Article and Find Full Text PDFZh Mikrobiol Epidemiol Immunobiol
July 1980
Guinea pigs were sensitized with different doses of homogenous Candida albicans cells introduced by 3 subcutaneous injections at intervals of 2--3 days. The allergic rearrangement in the animal body thus induced was found to depend on the dose of the preparation injected into the animals: the lowest dose of the antigen (0.1 mg) induced immediate allergic reaction, and doses 5--10 times higher induced double rearrangement i.
View Article and Find Full Text PDFZh Mikrobiol Epidemiol Immunobiol
May 1980
The results of experiments in using the basophil degranulation test and the leukocyte migration inhibition test for the characterization of mycogenous sensitization are presented. The model of mycogenous sensitization was created in guinea pigs by 3 injections of homogenized Candida albicans cells. Immediate allergic reaction is shown to develop earlier, as indicated by the results of the determination of homocytotropic antibody tites in passive skin anaphylaxis and by the results of the basophil degranulation test, than the appearance of delayed hypersensitivity detected by the leukocyte migration inhibition test.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!