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Amidst worldwide reports of adverse oral lesions subsequent to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination, the current systematic review planned to determine the prevalence of adverse oral events in adult individuals (≥18 years) after SARS-CoV-2 vaccination, emphasizing upon the type and dose of vaccine, time of onset, and underlying pathophysiology. The registered protocol (PROSPERO CRD42023421307), conforming with PRISMA guidelines, included an all-inclusive literature search through online databases, consisting of Scopus, PubMed/MEDLINE, Web of Science, Lilacs, Livivo, and PROSPERO, completed on 2 May 2023, followed by assessment of risk of bias by Joana Briggs Institute Evaluation Checklist. Due to the paucity of literature, case reports and case series were included.

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Article Synopsis
  • * Gingival disease-induced inflammation can damage connective tissue, bone, and soft tissue supporting teeth, resulting in looseness and instability.
  • * Regular dental hygiene can help prevent and reverse gingivitis, while non-plaque-induced lesions may indicate underlying systemic issues that require proper diagnosis and treatment.
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Herpetic gingivostomatitis and anogenital herpes are widely known manifestations of sexually transmitted herpesvirus infections. What is less recognized is the potential causative role of such infections in triggering immune-mediated skin disorders such as guttate psoriasis. We describe the case of a 23-year-old man with an acute episode of guttate psoriasis related to primary herpetic gingivostomatitis.

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  • * Both patients experienced painful oral ulcers and other complications requiring hospitalization, after ruling out other possible causes.
  • * Treatment included stopping chemotherapy and administering prednisolone, which improved the mucositis, but one patient faced a cancer recurrence after stopping chemotherapy, while the other patient was lost to follow-up.
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