Sight in babies: the pattern of research.

Nurs Mirror

Published: May 1982

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Epidemiology of ophthalmia neonatorum: a systematic review and meta-analysis.

BMC Pediatr

January 2025

Biomedical and Clinical Research Centre, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.

Purpose: To elucidate the global epidemiology of Ophthalmia Neonatorum (ON), as well as its causative organisms and their antibiotic susceptibility patterns.

Methods: A systematic review of studies reporting the epidemiology of ON was performed using four electronic databases: PubMed, Scopus, Web of Science, and Medline. Data were extracted and study-specific estimates were combined using meta-analysis to obtain pooled proportions.

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Article Synopsis
  • Neonatal protein C deficiency can lead to severe conditions like purpura fulminans and has a generally poor prognosis, especially regarding vision.
  • In a study of 38 survivors with biallelic PROC variants, a significant number suffered from severe visual impairments: 23 were totally blind, and only one had normal vision.
  • Prenatal intervention is crucial to enhance visual outcomes, as ocular lesions often present early in these cases, affecting the eyes before other organs.
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The treatment of demyelinating optic neuritis (DON) in pregnant patients is challenging, especially when there is poor or no response to intravenous methylprednisolone pulse (IVMP) therapy or adjunctive treatments such as intravenous immunoglobulin (IVIG) therapy. We herein report a case of a 28-year-old pregnant woman who experienced sequential severe vision loss in both eyes. She presented to a local hospital with the main complaint of sudden, painless vision loss in the left eye and was diagnosed with DON in the left eye.

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Object permanence allows infants to interact successfully with objects in the environment. What happens in the human infant brain when objects move in and out of sight? This study used high-density electroencephalography (hdEEG) to record induced oscillatory brain activities in 29 locomotor infants before, during, and after occlusion of a moving object traveling at different speeds. Temporal spectral evolution (TSE) showed that before and after the occlusion event, event-related synchronized (ERS) brain activity was observed, whereas event-related desynchronized (ERD) activity was detected when the car was hidden behind the occluder.

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Article Synopsis
  • The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
  • It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
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