The in vitro sensitivity against fosfomycin, oxacillin and penicillin G was tested in 65 Staphylococcus aureus strains, 71 coagulase negative staphylococci and 46 micrococci. Fosfomycin was very effective against staphylococci. Cross resistance with simultaneously tested penicillins could not be demonstrated. Fosfomycin was only partially effective against micrococci for which penicillin G was most effective.
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http://dx.doi.org/10.1055/s-2008-1070908 | DOI Listing |
Am J Infect Control
December 2024
Department of Microbiology, Vietnam National Children's Hospital, Hanoi, Vietnam.
Environ Sci Pollut Res Int
December 2024
Department of Medical Microbiology, Faculty of Medicine, Inonu University, Malatya, Turkey.
J Antimicrob Chemother
October 2024
Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA.
Unlabelled: Staphylococcus aureus (SA) is a leading cause of bloodstream infection. The liver represents the sentinel immune organ for clearance of bloodstream pathogens and eradication of intracellular SA from liver-resident macrophages (Kupffer cells, KCs) eliminates the likely pathogenic reservoir that contributes to persistent bacteraemia.
Objectives: We assessed antimicrobial activity at phagolysosome-mimicking pH, intracellular penetration, and SA eradication within KCs in vitro for clinically prescribed antistaphylococcal agents alone or in combination: vancomycin, daptomycin, ceftaroline, ceftobiprole, oritavancin, oxacillin, cefazolin; rifampin and fosfomycin.
New Microbiol
July 2024
Department of Infectious Diseases, ASFO Santa Maria degli Angeli Hospital of Pordenone, Pordenone, Italy.
Staphylococcus aureus bacteremia presents clinical complexities, with prolonged duration associated with unfavorable outcomes. This research delves into unconventional treatments, such as combinations involving daptomycin, oxacillin, ceftaroline, and fosfomycin, with the aim of swiftly sterilizing bloodstream infection to reduce complications. Our examination of 30 MSSA bacteremia patients with infective endocarditis uncovers differing results between single-agent therapies (oxacillin or daptomycin) and combined treatment plans.
View Article and Find Full Text PDFAntibiotics (Basel)
June 2024
Department of Veterinary Medicine and Animal Production, University of Naples "Federico II", Via Delpino 1, 80137 Naples, Italy.
, along with various other pathogenic bacteria, may show resistance against a broad spectrum of antibiotics. Evaluating the extent of resistance in harmful microorganisms like holds significant importance in crafting novel therapeutic strategies to mitigate or combat the rise of infections stemming from antibiotic-resistant bacteria. The present work aims to investigate the occurrence of antimicrobial resistance among strains in meat products (n = 173), seafood (n = 54), dairy products (n = 19), sauces (n = 2), confectionary products (n = 1), ready-to-eat rice dishes (n = 1), and food-processing environments (n = 19).
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