AI Article Synopsis
- A new non-invasive test combining biliary excretion scintigraphy with a mild meal has been developed to detect enterogastric bile reflux.
- The study found that 37 out of 73 patients exhibited significant reflux, with higher occurrences in those with past gastric surgery or gallbladder issues.
- Among healthy volunteers, only 2 showed probable reflux, suggesting that this condition is more prevalent in patients with existing gastrointestinal disorders.
Article Abstract
The study and clinical assessment of enterogastric bile reflux has been restricted for want of a simple non-invasive test for its detection and quantification. This paper describes such a test in which biliary excretion scintigraphy has been combined and a mild meal provocation. Two of 10 healthy volunteers studied showed probable reflux of approximately 5 per cent of total initial abdominal field activity. Among 73 patients studied, 37 patients showed definite reflux of up to 47 per cent. Reflux occurred in 19 of 22 post-gastric surgery patients and in 7 of 22 patients with peptic ulcer disease, gastritis or gastro-oesophageal reflux. None of 7 patients with 'non-specific' abdominal pain showed any reflux, but 11 of 22 patients with gallstone disease or previous cholecystectomy showed reflux of up to 35 per cent, including 9 of 11 patients with loss of gallbladder reservoir function.
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| http://dx.doi.org/10.1002/bjs.1800690215 | DOI Listing |
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