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Epidemiological trends of tetanus from East Delhi, India: a hospital-based study.

J Infect Public Health

November 2014

Department of Pediatrics, University College of Medical Sciences & Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.

Objective: To study the demographic profile, prognostic indicators, and mortality of tetanus patients and treatment outcomes following intramuscular anti-tetanus immunoglobulin (ATG) alone or combined intrathecal and intramuscular ATG.

Design: Retrospective study.

Setting: Inpatients from a tertiary care hospital.

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Objective: To determine the outcome of tetanus in neonates treated with intrathecal tetanus immunoglobulin in terms of mortality and hospital stay.

Study Design: Experimental study.

Place And Duration Of Study: Paediatric Unit I, Bahawal Victoria Hospital, Bahawalpur, from April 2004 to December 2007.

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This report discusses the issues involved in the diagnosis and management of tetanus. A 29-year-old female with a history of illicit drug use presented with progressive tetany secondary to an abscess on her forearm from subcutaneous injections. She was managed in the intensive care unit for 29 days and was discharged to the ward.

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Background: Tetanus is a major cause of mortality and morbidity in developing countries. Various modalities of treatment to prevent progression of the disease and alter its outcome have been tried. This study was designed to evaluate the role of intrathecal human anti-tetanus immunoglobulin (TIG) in the management of tetanus.

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In an attempt to lower the mortality rate of neonatal tetanus a study was undertaken to determine whether intrathecal serotherapy influences mortality from this disease. Sixty-six babies with tetanus neonatorum were studied. The mortality rate among babies who received intrathecal anti-tetanus serum (ATS) was 45% compared with 82% in the control group given intramuscular ATS (P congruent to 0.

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