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: To describe the clinical course and management of anterior uveitis complicated by ocular hypotony associated with Hodgkin lymphoma.: Case report.: Chart and multimodal imaging review, including ultrasound biomicroscopy, widefield fundus pictures, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography.

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Early Glaucoma Screening Using the Ibopamine Provocative Test.

J Glaucoma

May 2016

*Department of Ophthalmology, National Rehabilitation Institute of Mexico, Medicine School of The National Autonomous University of Mexico †Ophthalmologic Clinic Anzures, Mexican Glaucoma Society, México City ‡The National Institute of Public Health of Mexico, México.

Purpose: To evaluate the diagnostic ability of the ibopamine provocative test for early glaucoma detection.

Method: A sample of 44 patients with suspicious optic discs was recruited and compared with 37 controls with normal optic discs and no ocular pathology. The ibopamine test was performed in all patients who were then followed up with diagnostic tests for glaucoma, visual fields, and spectral-domain optical coherence tomography.

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Ibopamine challenge testing becomes negative following successful trabeculectomy surgery.

Clin Exp Ophthalmol

April 2016

Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.

Background: The ibopamine challenge test correlates well with a patient's peak diurnal intraocular pressure (IOP) measurement. We aimed to investigate the effect that a functioning trabeculectomy has on the ibopamine challenge test.

Design: Non-randomized prospective clinical trial evaluating a diagnostic test.

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Background: An ibopamine challenge is a novel technique for assessing glaucoma using ibopamine, a topical drug which temporarily increases aqueous production. We aimed to determine whether change in intraocular pressure (IOP) and/or optic cup volume (OCV) during the test differentiated between glaucoma patients at different stages of disease; namely, glaucoma suspects (GS), glaucoma patients who are stable (SG) and glaucoma patients who have demonstrated rapid progression (PG).

Design: Non-randomized clinical trial evaluating a diagnostic test.

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The purpose of the present review article is to update the information regarding pharmacokinetics of drugs in patients with heart failure that has accumulated since the last review article published in 1988 in Clinical Pharmacokinetics. Since this last review, our understanding of the pathophysiology of heart failure has changed from the cardio-renal model to the neuro-humoral model, and the pharmacologic approach to treatment of heart failure has been shifted from inotropic agents to those acting on the renin-angiotensin-aldosterone system. The pharmacologic agents now used for heart failure include many important classes of drugs, such as ACE inhibitors, angiotensin receptor blockers (antagonists) (ARBs), and mineralocorticoid receptor antagonists.

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