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Cognitive Impairment in Psychotic Disorders Is Associated with Brain Reductive Stress and Impaired Energy Metabolism as Measured by 31P Magnetic Resonance Spectroscopy.
Schizophr Bull
January 2025
Psychotic Disorders Division, McLean Hospital, Belmont, MA, United States.
Background And Hypothesis: Convergent evidence shows the presence of brain metabolic abnormalities in psychotic disorders. This study examined brain reductive stress and energy metabolism in people with psychotic disorders with impaired or average range cognition. We hypothesized that global cognitive impairment would be associated with greater brain metabolic dysregulation.
View Article and Find Full Text PDFDecreases in frequency-dependent intrinsic activity of the default mode network are associated with depression and cognition in patients with postacute sequelae of SARS-CoV-2 infection.
Brain Struct Funct
January 2025
Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China.
A significant proportion of patients who have recovered from COVID-19 suffer from persistent symptoms, referred to as "post-acute sequelae of SARS-CoV-2 infection (PASC)". Abnormal brain intrinsic activity has been observed in PASC patients, but the patterns of frequency-dependent intrinsic activity in the PASC and non-PASC (recovered COVID-19 patients without persistent symptoms) groups and their association with neuropsychiatric sequelae remain unclear in PASC. Twenty-nine PASC patients, 27 non-PASC subjects, and 31 healthy controls (HCs) were recruited.
View Article and Find Full Text PDFLive Music for Mental Health: A Pilot Study of How Concerts Influence Mental Health Stigma, Empathy, and Resource Utilization.
Health Promot Pract
January 2025
University of Louisville, Louisville, KY, USA.
Mental illness, affecting one in eight people worldwide, is often exacerbated by stigma-which can result in self-stigmatization, isolation, and loneliness and negatively impact access to health care, education, and social connection. Previous research has found that stigma is best reduced through a combination of education about the stigmatized population and intentional contact with individuals from that population. Studies also note the benefits of community-based, culturally-relevant interventions and cultural experiences such as live music.
View Article and Find Full Text PDFTwo Babies, Two Bonds: Challenges in Attachment Relationships in Twins.
Cureus
December 2024
Department of Child and Adolescent Psychiatry, Local Health Unit of Santo António, Porto, PRT.
The attachment relationship constitutes the first emotionally significant affective bond, usually between the infant and the mother, serving as a model for subsequent relationships. It is considered a vital component of social and emotional development in the early years and an important early indicator of infant mental health. In twins, the attachment process may exhibit unique characteristics, influenced by the dual parenting dynamic and the individual needs of each baby.
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