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Fuchs' uveitis syndrome: a 20-year experience in 466 patients.
Sci Rep
April 2024
Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Fuchs Uveitis Syndrome (FUS), also known as Fuchs Heterochromic Iridocyclitis, is a chronic form of uveitis characterized by mild inflammation primarily affecting one eye. This study aimed to investigate the clinical and epidemiological features of FUS in an Iranian population. A retrospective analysis was conducted on 466 patients diagnosed with FUS at an ophthalmology center affiliated with Isfahan University of Medical Sciences between 2003 and 2021.
View Article and Find Full Text PDFFactors associated with low prevalence of Fuchs' uveitis syndrome in Japan.
Front Med (Lausanne)
September 2022
Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan.
Article Synopsis
- The study aimed to investigate the low prevalence of Fuchs' uveitis syndrome (FUS) in Japan by reviewing medical records of 160 patients diagnosed with the condition at uveitis specialty facilities.
- Results showed that a significant number of patients were referred for idiopathic uveitis, cataracts, and glaucoma, with most patients experiencing unilateral symptoms and common findings like anterior inflammation and keratic precipitates.
- The conclusion suggests that the low prevalence of FUS in Japan may be due to misdiagnosis as milder conditions, affecting timely recognition and treatment of the syndrome.
Background: Fuchs heterochromic iridocyclitis is a chronic, unilateral iridocyclitis characterized by iris heterochromia. The gradual progression of the disease leads to the development of cataracts, glaucoma, and, occasionally, vitreous infiltration. The trigger for inflammation of the iris and ciliary body is still unknown.
View Article and Find Full Text PDFRubella Virus- and Cytomegalovirus-Associated Anterior Uveitis: Clinical Findings and How They Relate to the Current Fuchs Uveitis Syndrome Classification.
Front Ophthalmol (Lausanne)
June 2022
Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Ophthalmology, Berlin, Germany.
Rubella virus (RV) and cytomegalovirus (CMV) have both been implicated in anterior uveitis (AU). Clinical phenotypes can vary widely among both etiologies, including Fuchs uveitis syndrome (FUS) as a very distinct phenotype that has been associated with both RV and CMV. The Standardization of Uveitis Nomenclature (SUN) Working Group recently updated the classification criteria for FUS as unilateral AU, including either heterochromia or diffuse iris atrophy combined with stellate keratic precipitates as key findings.
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