Following transurethral resection of the tumour, 58 patients with histologically verified transitional cell carcinoma were subjected to local instillation treatment and oral vitamin A therapy. The instillation were carried out once a week over a 6-week period; cystoscopy with biopsy were carried out at 3-month intervals over an average period of 2.7 years. The vitamin A treatment appears to have no positive effect on persistent growth and on tendency to recurrence.

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