According to well documented histories a group of experts-endocrinologists determined the presence of one or another disease in 109 patients with different thyroid pathology. Two examinations were performed according to the clinical findings and on the basis of the same indices, added by results of the radioiodine test. Diagnostic informativity of different indices of the radioiodine test was evaluated according to the correlation (by means of calculation of the correlations) between the radiological parameter and the disease probability. It was concluded that the parameters of the routine research methods (131I absorption within 2, 4, 24 and 48 hours) are more informative than the values of more complicated variants of the radioiodine test. Informativity of the whole radiological and non-radiological findings was estimated, using a diagnostic coefficient method. It was shown that the role of radiological indices in making a correct diagnosis averages 17% and in cases of hypothyrosis and toxic forms of goiter this value increases up to 30%.
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BMC Med Imaging
December 2024
Department of Nuclear Medicine, Hospital 108, Hanoi, Vietnam.
Objective: Identifying prognostic markers for clinical outcomes is crucial in selecting appropriate treatment options for patients with radioiodine-refractory (RAI-R) differentiated thyroid carcinoma (DTC). The aim of this study was to investigate the prognostic value of clinico-pathological features and semiquantitative [F]FDG PET/CT metabolic parameters in predicting progression-free survival (PFS) in DTC patients with RAI-R.
Patients And Methods: This prospective cohort study included 110 consecutive RAI-R DTC patients who were referred for [F]FDG PET/CT imaging.
Future Oncol
December 2024
Department of Nuclear Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Aim: To investigate the prognostic value of pre-ablation stimulated thyroglobulin (ps-Tg) in children and adolescents with persistent differentiated thyroid cancer (DTC) following initial radioiodine therapy (RAI).
Materials & Methods: Patients were classified into "no clinical evidence of disease" (NED), "biochemical persistent disease" (BPD), and "structural/functional persistent disease" (S/FPD) groups, based on their therapeutic response to initial RAI. BPD patients were further categorized as incomplete response (IR) or Non-IR; S/FPD patients were categorized as remission or Non-remission.
BMC Surg
November 2024
Department of Nuclear Medicine, Tran Hung Dao Hospital (Hospital 108), Hanoi, Vietnam.
Background: [F]FDG PET/CT has been widely used as a diagnostic tool in detection and localization of recurrent non-avid radioiodine lesions in post-operative differentiated thyroid cancer (DTC) patients with elevated serum thyroglobulin but negative radioiodine whole-body scan (TENIS) syndrome. The aim of our study was to evaluate the role of [F]FDG PET/CT in prediction on outcomes of these DTC patients.
Methods: Post-operative DTC patients with TENIS syndrome were collected in the department of nuclear medicine, Hospital 108 from 2019 to 2023.
Mol Pharm
January 2025
Division of Applied RI, Korea Institute of Radiological & Medical Sciences, Seoul 01812, Korea.
Int J Nanomedicine
November 2024
Department of Nuclear Medicine, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Yangzhou, 225001, People's Republic of China.
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