Chlordane was, prior to regulatory action by EPA in 1976, an extensively used insecticide for both household and agricultural pest control purposes. It was readily available to the general public for many years; thus, human exposure, including poisonings, has been documented. A case reporting fatal chlordane ingestion with residue levels in various body tissues is presented. Analyses were performed by gas-liquid chromatography. The highest residue levels were reported in stomach contents, liver, brain, and adipose tissue.
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Signs and mechanisms of chlordane intoxication.
Biomed Environ Sci
September 1991
Chicago Institute for Neurosurgery and Neuroresearch, IL 60614.
Chlordane is a cyclopentadiene-derived insecticide that exerts its toxic action on the nervous system. In experimental animals the characteristic signs of acute toxicity are hypothermia, hyperexcitability, tremors and convulsions. In human, signs of acute chlordane toxicity are tremors and convulsions.
View Article and Find Full Text PDFChlordane was, prior to regulatory action by EPA in 1976, an extensively used insecticide for both household and agricultural pest control purposes. It was readily available to the general public for many years; thus, human exposure, including poisonings, has been documented. A case reporting fatal chlordane ingestion with residue levels in various body tissues is presented.
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