The hypothesis that addition of proline may save dietary protein for milk production was tested by administration of proline to two goats through a duodenal cannula. Because proline is synthesized by the mammary gland in vitro from arginine, the effect of proline supplementation on arginine uptake by the gland was tested in vivo. Arginine uptake, calculated from arterio-venous difference, dropped significantly in both animals, especially in the morning 1 h after milking, when a low-protein diet was fed. Milk production and total nitrogen in milk were not affected significantly by proline supplementation. A trend was toward decrease of milk orotic acid and an increase of milk fat due to proline supplementation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3168/jds.S0022-0302(83)81930-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Proline-Rich Antimicrobial Peptides from Invertebrates.
Molecules
December 2024
Department of Immunobiology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka 19 St., 20-033 Lublin, Poland.
Antimicrobial peptides (AMPs) constitute a large and diverse group of molecules with antibacterial, antifungal, antiviral, antiprotozoan, and anticancer activity. In animals, they are key components of innate immunity involved in fighting against various pathogens. Proline-rich (Pr) AMPs are characterized by a high content of proline (and arginine) residues that can be organized into Pro-Arg-Pro motifs.
View Article and Find Full Text PDFImpact of dietary supplementation of L-citrulline to meat goats during gestation on reproductive performance.
J Anim Sci Biotechnol
January 2025
Department of Animal Science, Texas A&M University, College Station, Texas, 77843, USA.
Background: Meat goat production is a worldwide industry with products such as meat, milk, soap, and fiber being produced. There are approximately 2.6 million meat goats in the United States.
View Article and Find Full Text PDFSLC7A5 is required for cancer cell growth under arginine-limited conditions.
Cell Rep
January 2025
Department of Biochemistry, University of Utah, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:
Tumor cells must optimize metabolite acquisition between synthesis and uptake from a microenvironment characterized by hypoxia, lactate accumulation, and depletion of many amino acids, including arginine. We performed a metabolism-focused functional screen using CRISPR-Cas9 to identify pathways and factors that enable tumor growth in an arginine-depleted environment. Our screen identified the SLC-family transporter SLC7A5 as required for growth, and we hypothesized that this protein functions as a high-affinity citrulline transporter.
View Article and Find Full Text PDFInfluence of indole acetic acid, arginine and mango fruit waste biochar on nutrients, chlorophyll contents and antioxidants of Fenugreek in salt affected soil.
Sci Rep
January 2025
Department of Botany and Microbiology, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia.
Salinity stress disrupts water uptake and nutrient absorption, causing reduced photosynthesis, stunted growth, and decreased crop yields in plants. The use of indole acetic acid (IAA), arginine (AN), and mango fruit waste biochar (MFWB) can be effective methods to overcome this problem. Indole acetic acid (IAA) is a natural auxin hormone that aids cell elongation and division, thereby increasing plant height and branching.
View Article and Find Full Text PDFPositive feedback between arginine methylation of YAP and methionine transporter SLC43A2 drives anticancer drug resistance.
Nat Commun
January 2025
Department of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai, China.
Yes-associated protein (YAP) activation confers resistance to chemotherapy and targeted therapy. Methionine participates in cellular processes by converting to methyl donor for the methylation of DNA, RNA and protein. However, it remains unclear whether methionine affects drug resistance by influencing YAP activity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!