Although Lown grading system of ventricular premature complexes (VPCs) has important conceptual shortcomings and has shown severe limitations in either cross-sectional or longitudinal studies, this classification is still the most well-known and used method to characterize the arrhythmologic ventricular pattern of the individual patient. We have looked at a modification of VPCs Lown grading scheme to correct the defects and to make the use of the classification more accurate. Our proposal is based on maintenance of 5 classes--similar to those of Lown original classification--to which we have assigned a score from 0 to 60. We have also introduced many sub-classes, each with a definite score, to better characterize the type of arrhythmic event. The sum of the score of the highest class and the score of every subclass furnishes the final score. This score is a direct index of the importance of the ventricular arrhythmias and seems to be useful for statistical evaluation of the anti-arrhythmic therapy and for follow-up studies, as confirmed by preliminary clinical results obtained through the use of this new VPCs classification.
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JTCVS Open
June 2024
Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.
J Vet Cardiol
June 2024
Department of Veterinary Medical Sciences, Alma Mater Studiorum - University of Bologna, via Tolara di Sopra 50, 40064, Ozzano dell'Emilia, Italy.
Introduction/objective: Studies on the use of amiodarone or sotalol are limited in dogs. Therefore, this study aimed to provide data on the efficacy and safety of these drugs in dogs with ventricular tachyarrhythmia (VT) and/or supraventricular tachyarrhythmia (SvT).
Animals, Materials, And Methods: Dogs with VT and/or SvT treated with amiodarone or sotalol as a first-line therapy were retrospectively evaluated.
Egypt Heart J
March 2024
Cardiology Department, Faculty of Medicine, Alexandria University, Champlion Street, El Azarita, Alexandria, Egypt.
Background: Left ventricular hypertrophy (LVH) is associated with an increased risk of ventricular arrhythmias and cardiovascular mortality. The study objective was to investigate the effect of LVH severity on the complexity and severity of ventricular arrhythmias among a subset of Egyptian hypertensive patients.
Results: The study cohort consisted of 60 hypertensive patients with LVH as diagnosed by echocardiography.
Arch Cardiovasc Dis
November 2023
Hôpital privé de La Louvière, 69, rue de La Louvière, 59000 Lille, France.
Background: Mitral annular disjunction (MAD) and the Pickelhaube sign are identified as risk factors for malignant ventricular arrhythmias (VAs) and sudden cardiac death in adults with mitral valve prolapse (MVP); their prevalence and consequences in children have never been studied.
Objectives: To determine the proportion of MAD in children with MVP, and its potential link with VAs.
Methods: A cohort of 49 consecutive children (mean age 12.
Exp Biol Med (Maywood)
April 2023
Wuxi No.2 People's Hospital, The Affiliated Wuxi Clinical College of Nantong University, Wuxi 214002, China.
Percutaneous coronary intervention (PCI) has been widely used in the alleviation of myocardial ischemia in patients with acute coronary syndrome (ACS). However, the incidence of reperfusion arrhythmia (RA) after PCI is high, which seriously affects the prognosis of ACS patients. Therefore, this study aimed to study the predictive value of serum HIF-1α and VEGF levels before PCI for RA in ACS patients post PCI.
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