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Effects of Replacing Inorganic Sources of Copper, Manganese, and Zinc with Different Organic Forms on Mineral Status, Immune Biomarkers, and Lameness of Lactating Cows.
Animals (Basel)
January 2025
Sino-US Joint Lab on Nutrition and Metabolism of Ruminant, Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
(Objectives) The objectives of this study were to evaluate the effect of half-replacement of the supplementary sulfate sources of Cu, Mn, and Zn with methionine-hydroxy-analog-chelated (MHAC) mineral or amino-acid-complexed (AAC) mineral forms in diets on the mineral status, blood immune biomarkers, and lameness of lactating cows. (Methods) Sixty multiparous Holstein cows (158 ± 26 days in milk; body weight: 665 ± 52 kg; milk yield: 32 ± 7 kg/day) were randomly assigned into one of three dietary treatments ( = 20 per group): (1) MHAC: 50% replacement of sulfate minerals with MHAC forms. (2) AAC: 50% replacement of sulfate minerals with AAC forms.
View Article and Find Full Text PDFCase report: Rituximab combined with plasma exchange treatment for systemic lupus erythematosus complicated with thrombotic microangiopathy and non-cirrhotic portal hypertension.
Front Immunol
January 2025
Department of Rheumatology and Immunology, the Second Affiliated Hospital of Xiamen Medical College, Xiamen, China.
Introduction: Systemic lupus erythematosus (SLE) complicated by thrombotic microangiopathy (TMA) and non-cirrhotic portal hypertension (NCPH) is rare. We present a case of a female patient with SLE who developed TMA and NCPH and responded positively to rituximab and plasma exchange treatment.
Case Description: A 53-year-old woman was admitted with 6 h of confusion.
Dysfunctional copper homeostasis in affects genomic and neuronal stability.
Redox Biochem Chem
December 2024
Food Chemistry with Focus on Toxicology, Faculty of Mathematics and Natural Sciences, University of Wuppertal, Germany.
While copper (Cu) is an essential trace element for biological systems due to its redox properties, excess levels may lead to adverse effects partly due to overproduction of reactive species. Thus, a tightly regulated Cu homeostasis is crucial for health. Cu dyshomeostasis and elevated labile Cu levels are associated with oxidative stress and neurodegenerative disorders, but the underlying mechanisms have yet to be fully characterized.
View Article and Find Full Text PDFAppeasing Substance Administration at Feedlot Entry Impacted Temperament, Pen Behavior, Immunocompetence, and Meat Quality of Beef Heifers.
Animals (Basel)
December 2024
Unidade Universitária de Aquidauana, Universidade Estadual de Mato Grosso do Sul, Aquidauana 79200-000, MS, Brazil.
This experiment evaluated the effects of bovine appeasing substance (BAS) administration at feedlot entry on growth, temperament, inflammation, response to vaccination, behavior, carcass characteristics, and meat quality of beef heifers. Thirty heifers were weaned and assigned to (d 0): (1) BAS (n = 15; SecureCattle; IRSEA Group) or (2) Saline (n = 15). On d 0, heifers were also vaccinated against respiratory diseases and slaughtered on d 150.
View Article and Find Full Text PDFPrecise and panoramic study on the nutritional components of specific milk of goats and sheep.
Food Chem
February 2025
College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. Electronic address:
Article Synopsis
- - The study examined the milks of humans, goats, sheep, and pigs using advanced techniques like metabolomics, lipidomics, and proteomics to find differences among them and similarities to human milk for infant formula development.
- - Key findings revealed that goat milk had high levels of lactoperoxidase, inosine, and allantoin, while sheep milk showed higher concentrations of ceruloplasmin and alpha-ketoglutarate.
- - Additionally, both goat and sheep milks had a relatively high amount of linoleic acid (LA), and pig milk was noted for having significant levels of milk fat globule EGF factor 8 protein.
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