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Enhancing Virus Filter Performance Through Pretreatment by Membrane Adsorbers.
Membranes (Basel)
January 2025
Ralph E. Martin Department of Chemical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Virus filtration is used to ensure the high level of virus clearance required in the manufacture of biopharmaceutical products such as monoclonal antibodies. Flux decline during virus filtration can occur due to the formation of reversible aggregates consisting of self-assembled monomeric monoclonal antibody molecules, particularly at high antibody concentrations. While size exclusion chromatography is generally unable to detect these reversible aggregates, dynamic light scattering may be used to determine their presence.
View Article and Find Full Text PDFCaustic recovery from caustic-containing polyethylene terephthalate (PET) washing wastewater generated during the recycling of plastic bottles.
Sci Rep
January 2025
Department of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
To prevent water scarcity, wastewater must be discharged to the surface or groundwater after being treated. Another method is to reuse wastewater in some areas after treatment and evaluate it as much as possible. In this study, it is aimed to recover and reuse the caustic (sodium hydroxide, NaOH) used in the recycling of plastic bottles from polyethylene terephthalate (PET) washing wastewater.
View Article and Find Full Text PDFSafety and efficacy of therapeutic plasma exchange in pediatric neuro-immunological diseases.
Adv Med Sci
January 2025
Department of Pediatric Nephrology and Hypertension, Jagiellonian University Medical College, Cracow, Poland. Electronic address:
Purpose: Therapeutic plasma exchange (TPE) is the treatment of choice in various neuro-immunological disorders in pediatric populations. This study assesses the safety and efficacy of TPE in this demographic.
Materials And Methods: A single-center, retrospective cohort study involving pediatric patients who experienced neuro-immunological events and underwent TPE procedures at a tertiary referral center was conducted.
Tolerability of Sodium-Glucose Co-transporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Retrospective Cohort Study.
Cureus
December 2024
Department of Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, SAU.
Background Sodium-glucose co-transporter 2 (SGLT2) inhibitors are an emerging treatment for type 2 diabetes mellitus (T2DM). The effect and tolerability of SGLT2 inhibitors in patients with T2DM, especially related risk factors and susceptible populations, are an area of ongoing research. Aim The aim of this study was to evaluate the tolerability of SGLT2 inhibitors, particularly the risk associated with urogenital infection, in patients with T2DM.
View Article and Find Full Text PDFReverse osmosis membrane fouling caused by typical surfactants in the integrated circuit industry: Fouling mechanism and control strategies.
Water Res
January 2025
Kurita Water Industries Ltd., Nakano-ku, Tokyo 164-0001, Japan.
In the integrated circuit manufacturing process, reverse osmosis (RO) membranes are widely used for wastewater reclamation. However, fouling by typical surfactants significantly reduces membrane efficiency and lifespan. This study investigates the fouling mechanisms of typical surfactants-cetyl trimethyl ammonium bromide (CTAB, cationic), sodium dodecyl sulfate (SDS, anionic), and polyoxyethylene octyl phenyl ether (TX, nonionic)-on RO membranes.
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