Phototherapy results in transformation of bilirubin to more water-soluble isomers. The efficacy of monochromatic visible light from 350 to 550 nm in the fastest photoisomerization reaction was quantitated by high-pressure liquid chromatography. The most effective wavelengths in vitro (i.e., leading to greater than 25% photoisomer) were in the blue spectrum from approximately 390 to 470 nm. Green light (530 nm) was not only ineffective for production of photoisomer, but capable of reversing the reaction. The results indicate that any clinically useful phototherapy unit must include the blue portion of the visible spectrum, and suggest that the effectiveness of phototherapy may be increased by elimination of green light.
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http://dx.doi.org/10.1016/s0022-3476(83)80370-9 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
State Key Laboratory of Protein and Plant Genetic Engineering, School of Life Science, Peking University, Beijing 100871, People's Republic of China.
Phycobilisomes (PBS) are the major photosynthetic light-harvesting complexes in cyanobacteria and red algae. While the structures of PBS have been determined in atomic resolutions, how PBS are attached to the reaction centers of photosystems remains less clear. Here, we report that a linker protein (LcpA) is required for the attachment of PBS to photosystem II (PSII) in the cyanobacterium sp.
View Article and Find Full Text PDFSmall
January 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, China.
The development of aqueous zinc metal batteries (AZMBs) is hampered by dendrites and side reactions induced by reactive HO. In this study, a hydrated eutectic electrolyte with restrictive water consisting of zinc trifluoromethanesulfonate (Zn(OTf)), 1,3-propanediol (PDO), and water is developed to improve the stability of the anode/electrolyte interface in AZMBs via the formation of a water-deficient interface. Additionally, PDO participates in the Zn solvation structure and inhibits the movement of water molecules.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Henan Key Laboratory of Natural Medicine Innovation and Transformation, Henan University, Kaifeng, Henan 475004, PR China.
Recent advancements in green and sustainable platforms, particularly visible light-driven photocatalysis, have spurred significant progress in radical chemistry, enabling the efficient synthesis of important molecules from simple and readily available feedstocks under mild conditions. However, the rapid orbital flipping and high reactivity of radicals pose substantial challenges for achieving precise enantiocontrol in stereocenter formation via radical coupling. In this study, we present a generic and efficient strategy that modulates this elusive approach, facilitating enantiocontrollable protonation through 1,3-boron migration.
View Article and Find Full Text PDFAdv Mater
January 2025
Zhejiang Provincial Engineering Research Center of Energy Optoelectronic Materials and Devices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, 315201, P. R. China.
Herein, a parallel "bifunctional group" modulation method is proposed to achieve controlled modulation of the emission wavelength and full-width at half-maximum (FWHM) values. As a result, three proof-of-concept emitters, namely DBNDS-TPh, DBNDS-DFPh, and DBNDS-CNPh, are designed and synthesized, with the first functional dibenzo[b,d]thiophene unit concurrently reducing the bandgap and elevate their triplet state energy. A second functional group 1,1':3',1″-triphenyl, and electron acceptors 1,3-difluorobenzene and benzonitrile, respectively, to deepen the HOMO and LUMO levels.
View Article and Find Full Text PDFHydrothermal carbonization (HTC) of carbohydrates has been reported as a sustainable and green technique to produce carbonaceous micro- and nano-materials. These materials have been developed for several applications, including catalysis, separation science, metal ion adsorption and nanomedicine. Carbon nanoparticles (CNPs) obtained through HTC are particularly interesting for the latter application since they exhibit photothermal properties when irradiated with near-infrared (NIR) light, act as an antioxidant by scavenging reactive oxygen species (ROS), and present good colloidal stability and biocompatibility.
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