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A systematic in vitro study of the effect of normoglycaemic and hyperglycaemic conditions on the biochemical and cellular interactions of clinically-available wound dressings with different physicochemical properties.
PLoS One
January 2025
Centre for Regenerative Medicine and Devices, University of Brighton, Brighton, United Kingdom.
Diabetic foot, leg ulcers and decubitus ulcers affect millions of individuals worldwide leading to poor quality of life, pain and in several cases to limb amputations. Despite the global dimension of this clinical problem, limited progress has been made in developing more efficacious wound dressings, the design of which currently focusses on wound protection and control of its exudate volume. The present in vitro study systematically analysed seven types of clinically-available wound dressings made of different biomaterial composition and engineering.
View Article and Find Full Text PDFFrailty determinants in heart failure: Inflammatory markers, cognitive impairment and psychosocial interaction.
ESC Heart Fail
January 2025
Division of Research Methodology, Department of Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wrocław, Poland.
Aims: This study aimed to identify factors associated with frailty in heart failure (HF) patients, focusing on demographic, biochemical and health-related variables. It also explored the correlation between frailty and comorbidities such as malnutrition, cognitive impairment and depression, assessing how these factors interact to influence frailty risk.
Methods: A total of 250 HF patients (mean age 73.
Environmental monitoring of La Concordia mine (Salta province, Argentina): assessing heavy metal bioaccumulation and physiological responses of Parastrephia quadrangularis.
Environ Monit Assess
January 2025
Instituto de Fisiología Vegetal (INFIVE-CCT La Plata), La Plata, Buenos Aires, Argentina.
The Puna region is distinguished by its extreme environmental conditions and highly valuable mining resources. However, the unregulated management of mine tailings poses a significant threat to the ecological integrity of this region. This study assesses the environmental impacts of mine tailings at La Concordia mine (Salta province, Argentina) and examines the physiological and biochemical adaptations of Parastrephia quadrangularis (Meyen) Cabrera that enable its survival under this extreme conditions.
View Article and Find Full Text PDFAdulteration in edible oil (mustard oil) and ghee; detection and their effects on human health.
Int J Biochem Mol Biol
December 2024
Gene Expression and Signaling Lab, Department of Zoology, Mahatma Gandhi Central University Motihari 845401, Bihar, India.
Edible oils and ghee are vital parts of our daily culinary practices. In recent years, owing to heightened demand in the domestic and global markets, consistent reports regarding the adulteration of edible oils and ghee with substandard ingredients have been reported. Adulteration in edible oils is widespread, with distinctive contaminants, including cottonseed, mineral, and lower-cost oils like palm olein.
View Article and Find Full Text PDFImpact of high hemoglobin levels on carotid artery intima-media thickness and its predictive value for hypertension in high-altitude areas: a real-world study.
Front Cardiovasc Med
January 2025
Hyperbaric Oxygen, Chengdu First People's Hospital, Chengdu, Sichuan, China.
Background And Purpose: The hemoglobin levels in the peripheral blood of individuals living at high altitudes are significantly higher than normal levels. These levels are closely associated with atherosclerosis and cardiovascular events. This study aimed to investigate the correlation between hemoglobin levels in the peripheral blood and hypertension in high-altitude regions, providing a basis for preventing and treating primary hypertension in these regions.
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