Electron and histochemical techniques were used to study the localization of carnitine acetyltransferase (CAT) in different tissues of intact and fasting rats (at the 5th day after keeping the animals without food, with the drinking regimen remaining unchanged). The enzyme was discovered in mitochondria and microbodies of cardiomyocytes, hepatocytes and fibers of the skeletal muscle of intact rats. In fasting animals, CAT was identified not only in mitochondria and microbodies of cardiomyocytes and hepatocytes but also in membranes surrounding fat inclusions as well as in the plasmalemma of adipocytes. On fasting the content of microbodies in the cells was higher than that in normality.
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