AI Article Synopsis
- The national BCG vaccine shows promise as an oncolytic and immunotherapeutic agent against undifferentiated sarcoma induced by a specific adenovirus in hamsters.
- Preliminary findings indicate that administering the vaccine before tumor formation leads to significant positive outcomes.
- However, injecting the vaccine directly into existing tumors did not lead to any noticeable tumor regression.
Article Abstract
The oncolytic and immunotherapeutic effect of the national BCG vaccine with respect to undifferentiated sarcoma of hamster induced by the highly oncogenic adenovirus of green monkeys SA7(C8) was studied. Preliminary data on significant positive effect of the vaccine inoculated before tumor formation were obtained. A single inoculation of the vaccine into tumors did not result in tumor regression in any of the cases.
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