The whole blood viscosity and the tissue oxygen balance were studied in rats and rabbits with alloxan diabetes. An augmentation of the blood viscosity was seen in female rats during diabetes latent period after injecting alloxan in a dose of 100 mg/kg. The blood viscosity is 3 times as high in diabetes, produced by the injection of alloxan in a dose of 200 mg/kg, and is characterized by severe hyperglycemia, simultaneously the tissue oxygen balance alteration is observed. Similarly the blood rheological properties and oxygen-transport functions are changed in female rabbits after injecting alloxan in a dose of 150 mg/kg. The blood viscosity of male rabbits with alloxan diabetes does not differ from that of the controls.
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