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Green tea fermented by Ganoderma lucidum presented anti-obesity properties via enhanced thermogenesis in vitro and on C57BL/6J mice.
Food Res Int
April 2025
Key Laboratory of Tea Science of Ministry of Education, National Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Key Laboratory for Evaluation and Utilization of Gene Resources of Horticultural Crops, Ministry of Agriculture and Rural Affairs of China, Hunan Agricultural University, Changsha, Hunan 410128, China. Electronic address:
High-fat diets contribute to obesity and metabolic disorders. Ganoderma lucidum is renowned for its abundant bioactive compounds and diverse pharmacological effects. Green tea fermented by G.
View Article and Find Full Text PDFToward near real-time precise supervision of radiofrequency ablation for liver fibrosis using hyperspectral imaging.
Spectrochim Acta A Mol Biomol Spectrosc
March 2025
Department of Biomedical Engineering, Military Technical College, Cairo, Egypt.
Background And Aims: Chronic liver diseases pose a significant global health concern, ranking as the 11th leading cause of death worldwide. It often progresses to organ fibrosis and severe complications such as portal hypertension and cirrhosis. Liver transplantation is the most effective treatment for such diseases, however, the persistent shortage of donors highlights the need for alternatives.
View Article and Find Full Text PDFEdgeworthia gardneri (Wall.) Meisn Mitigates CCL4-induced liver injury in mice by modulating gut microbiota, boosting antioxidant defense, and reducing inflammation.
Ecotoxicol Environ Saf
March 2025
College of Veterinary Medicine, Yunan Agricultural University, Kunming 650201, PR China; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:
Herbal medicine has become an area of growing global scientific interest. The prime objective of this study was to investigate the protective role of Edgeworthia gardneri (Wall.) Meisn (EGM polysaccharide) against carbon tetrachloride (CCl)-induced liver injury in mice.
View Article and Find Full Text PDFEthanolic extract of leaves alleviates insulin resistance by modulating oxidative stress and inflammation in albino rats exposed to heavy metal mixture.
Nat Prod Res
March 2025
Department Biochemistry, Ebonyi State University, Abakaliki.
Exposure to heavy metals significantly contributes to insulin resistance, a major factor in type 2 diabetes. This study investigated the antioxidant and therapeutic potential of ethanol leaf extract of in mitigating heavy metal-induced insulin resistance, oxidative stress and inflammation in albino rats. Thirty rats were divided into five groups: Groups I and II received normal saline and a lead-mercury mixture, respectively, while Groups III, IV and V were treated with the extract (200, 400 and 600 mg/kg) for four weeks after exposure.
View Article and Find Full Text PDFDeuterium Metabolic Imaging of the Human Abdomen at Clinical Field Strength.
Invest Radiol
March 2025
From the Department of Radiology, University of Cambridge, Cambridge, UK (P.W., M.A.M., I.H.-M., J.R.B., M.J.Z.-M., A.G., E.L., M.W., F.A.G.); University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK (M.A.M., F.A.G.); and GE HealthCare, Munich, Germany (R.F.S.).
Objectives: The aim of the study was to translate abdominal deuterium metabolic imaging (DMI) to clinical field strength by optimizing the radiofrequency coil setup, the administered dose of deuterium (2H)-labeled glucose, and the data processing pipeline for quantitative characterization of DMI signals over time. This was assessed in the kidney and liver to establish a basis for routine clinical studies in the future.
Materials And Methods: 5 healthy volunteers were recruited and imaged on 2 or 3 separate occasions, with varying doses of 2H-glucose: 0.
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