AI Article Synopsis

  • The study examined various biological and chemical tests used to evaluate the toxicity of synthetic polymers, noting that the tests often showed no consistent correlation with each other.
  • The specific tests included sperm cell motility, tissue culture inhibition, intracutaneous tests, optical absorption in a certain wavelength range, and the assessment of reducing impurities.
  • As a result, the overall toxicity assessment of the synthetic polymers relies on a cumulative evaluation of these individual test results, which need to be expressed in arbitrary units for accuracy.

Article Abstract

Some of the biological and chemical tests used in toxicological evaluation of synthetic polymers were correlated. The individual tests (sperm cell motility, tissue culture inhibition, intracutaneous test, optical absorption at 220-360 nm, reducing impurities) did not mutually correspond. The final estimation of the tested device is assessed as a sum of these units. Therefore, it is necessary to evaluate the results of the individual tests in arbitrary units.

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Source
http://dx.doi.org/10.1016/0142-9612(83)90051-0DOI Listing

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