Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Personalized treatment approaches in hepatocellular carcinoma.
Arab J Gastroenterol
January 2025
Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt; Liver Disease Research Center, College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia. Electronic address:
Personalized medicine is an emerging field that provides novel approaches to disease's early diagnosis, prevention, treatment, and prognosis based on the patient's criteria in gene expression, environmental factors, lifestyle, and diet. To date, hepatocellular carcinoma (HCC) is a significant global health burden, with an increasing incidence and significant death rates, despite advancements in surveillance, diagnosis, and therapeutic approaches. The majority of HCC lesions develop in patients with liver cirrhosis, carrying the risks of mortality associated with both the tumor burden and the cirrhosis.
View Article and Find Full Text PDFSchool-based environment and physical activity in adolescents: A systematic review and meta-analysis.
Prev Med
January 2025
School of Sport Science, Beijing Sport University, Beijing 100091, China; Key Laboratory of Sports and Physical Health Ministry of Education, Beijing Sport University, Beijing 100091, China. Electronic address:
Objective: This study aimed to evaluate the effectiveness of school environmental factors in promoting adolescents' physical activity.
Methods: A systematic search of five databases (PubMed, Embase, Web of Science, EBSCO, and Cochrane Library) was conducted from the earliest available records up to September 2023. Meta-analyses were performed for each school environmental factor, provided that at least two studies reported on the association between that factor and adolescents' physical activity.
Neural markers of human aggression and cooperation are influenced by zero-sum or non-zero-sum groups.
Int J Psychophysiol
January 2025
Faculty of Psychology, Beijing Normal University, Beijing, China; School of Economics and Management, Fuzhou University, Fuzhou, China. Electronic address:
Cooperation and competition in social interaction are important to social development. There are many studies examining the neural mechanism underlying these behaviors; however, little is known about the potential role of payoff norms in social interactions. This study introduced two distinct payoff norms: zero-sum (ZS) and non-zero-sum (NZS).
View Article and Find Full Text PDFWeighing In: Glucagon-Like Peptide-1 Receptor Agonism for Persons With HIV.
Top Antivir Med
December 2024
Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Weight gain among persons with HIV PWH) on contemporary antiretroviral therapy (ART) can extend beyond an initial return-to-health phenomenon and lead to overweight/obesity in the first 1 to 2 years, resulting in enhanced cardiometabolic risk. Factors that may contribute to increased weight gain include specific ART regimens (those initiating dolutegravir and tenofovir alafenamide or withdrawing tenofovir disoproxil and efavirenz), women with HIV, and certain virologic factors including lower baseline CD4 count and higher HIV viral load. Weight reduction starting at 5% body weight confers metabolic protection, such as improved hypertension and dysglycemia.
View Article and Find Full Text PDFStructures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.
Immunity
January 2025
Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA. Electronic address:
Cyclic nucleotide GMP-AMP (cGAMP) plays a critical role in mediating the innate immune response through the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway. Recent studies showed that ATP-binding cassette subfamily C member 1 (ABCC1) is a cGAMP exporter. The exported cGAMP can be imported into uninfected cells to stimulate a STING-mediated innate immune response.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!