In 70 total hip arthroplasties exchanged because of mechanical loosening of the stem prosthesis, localized bone resorption or scalloping was found in 33 cases. In 19 of the 33 cases the process started at the level of the tip of the stem, which in 15 cases was found to be in direct contact with cortical bone as observed in the radiographs obtained immediately after the primary surgery. In 37 failures without scalloping this metal-to-bone contact was less common. It is concluded that localized bone resorption may occur as a result of mechanical stress and in the absence of deep infection. It is also suggested that the phenomenon might be avoided by proper cementing technique and centering of the tip of the stem, perhaps with the help of a centering device.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/17453678308996591 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mechanisms and new advances in the efficacy of plant active ingredients in tendon-bone healing.
J Orthop Surg Res
January 2025
The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, No.41 Linyin Road, Baotou, Inner Mongolia, 014010, China.
The tendon-bone interface, known as the tenosynovial union or attachment, can be easily damaged by excessive exercise or trauma. Tendon-bone healing is a significant research topic in orthopedics, encompassing various aspects of sports injuries and postoperative recovery. Surgery is the most common treatment; however, it has limited efficacy in promoting tendon-bone healing and carries a risk of postoperative recurrence, necessitating the search for more effective treatments.
View Article and Find Full Text PDFLangerhans cell histiocytosis in children: the value of ultrasound in diagnosis and follow-up.
BMC Med Imaging
January 2025
Department of Ultrasound Medicine, First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Background: Langerhans cell histiocytosis (LCH) is a rare disease, most prevalent in children. Ultrasound is a noninvasive, cheap, and widely available technique. However, systematic elucidation of sonographic features of LCH and treatment related follow-up are relatively few, resulting in overall underestimation of the clinical value of ultrasound in diagnosing and monitoring LCH.
View Article and Find Full Text PDFLeveraging survival analysis and machine learning for accurate prediction of breast cancer recurrence and metastasis.
Sci Rep
January 2025
Center for Informatics Science (CIS), School of Information Technology and Computer Science, Nile University, 26th of July Corridor, Sheikh Zayed City, Giza, 12588, Egypt.
Breast cancer, with its high incidence and mortality globally, necessitates early prediction of local and distant recurrence to improve treatment outcomes. This study develops and validates predictive models for breast cancer recurrence and metastasis using Recurrence-Free Survival Analysis and machine learning techniques. We merged datasets from the Molecular Taxonomy of Breast Cancer International Consortium, Memorial Sloan Kettering Cancer Center, Duke University, and the SEER program, creating a comprehensive dataset of 272, 252 rows and 23 columns.
View Article and Find Full Text PDFIn situ osteogenic activation of mesenchymal stem cells by the blood clot biomimetic mechanical microenvironment.
Nat Commun
January 2025
Institute for Stem Cell & Regenerative Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 710004, Xi'an, China.
Blood clots (BCs) play a crucial biomechanical role in promoting osteogenesis and regulating mesenchymal stem cell (MSC) function and fate. This study shows that BC formation enhances MSC osteogenesis by activating Itgb1/Fak-mediated focal adhesion and subsequent Runx2-mediated bone regeneration. Notably, BC viscoelasticity regulates this effect by modulating Runx2 nuclear translocation.
View Article and Find Full Text PDFDevelopment of multifunctional PAA-alginate-carboxymethyl cellulose hydrogel-loaded fiber-reinforced biomimetic scaffolds for controlled release of curcumin.
Int J Biol Macromol
January 2025
MEMS and Nanotechnology Laboratory, School of Mechanical Engineering, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Republic of Korea; Advanced Medical Device Research Center for Cardiovascular Disease, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Republic of Korea; Center for Next-Generation Sensor Research and Development, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, Republic of Korea. Electronic address:
Critical-sized bone defects in osteosarcoma treatment demand multifunctional scaffolds that must effectively integrate two key functions, promoting osteogenesis and delivering targeted chemoprevention. This study introduces a dual-component system featuring pH-responsive hydrogels and hydroxyapatite-based fiber-reinforced biomimetic scaffolds designed for controlled and localized curcumin delivery, while addressing its solubility and stability issues. The hydrogel system comprises a double network of polyacrylic acid, sodium alginate, carboxymethyl cellulose, and potato starch, specifically modified to encapsulate curcumin.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!