A long-axis real-time ultrasonic transrectal probe was utilized in transperineal biopsies to detect three nonpalpable prostate cancers. It was found that ultrasonically guided percutaneous perineal biopsy allows for the accurate placement of the biopsy needle tip into suspicious areas of the prostate. Ultrasonographic examination prior to biopsy is recommended to provide confirmation of palpable masses and to reveal other suspicious but not clinically suspected areas.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.7863/jum.1983.2.4.165 | DOI Listing |
Int J Urol
January 2025
Department of Urology, Nara Medical University, Kashihara, Nara, Japan.
Objective: We investigated the impact of intraoperative tumor capsule injury (TCI) during robot-assisted partial nephrectomy (RAPN) or laparoscopic partial nephrectomy (LPN) on oncological outcomes, as well as underlying factors of intraoperative TCI for improving surgical outcomes.
Methods: A total of 253 patients who underwent RAPN or LPN between 2010 and 2022 were retrospectively analyzed and were divided into two groups: non-TCI and TCI groups. The background was compared between two groups.
Int J Urol
January 2025
Department of Urology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
Objectives: This study aimed to investigate the association between the type of prostate biopsy and the occurrence of rectal wall infiltration (RWI) with hydrogel spacer placement in patients undergoing radiotherapy for prostate cancer.
Methods: A retrospective study was conducted involving 175 patients who received hydrogel spacer placement before radiotherapy at the National Cancer Center East Hospital, between October 2021 and December 2023. The patients were categorized based on the type of prostate biopsy: transperineal and transrectal.
Curr Pharm Biotechnol
January 2025
Department of Urology & Andrology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan.
Introduction: Prostate cancer is an androgen-dependent malignancy, and the use of androgen deprivation therapies frequently results in treatment resistance, relapse, and the development of aggressive castration-resistant tumors. Patchouli alcohol, a tricyclic sesquiterpene derived from Pogostemon cablin of the Labiatae family, has demonstrated potential in modulating inflammatory responses and tumor progression. This study aimed to investigate the mechanisms through which patchouli alcohol influences inflammatory pathways associated with prostate cancer using bioinformatics and experimental validation.
View Article and Find Full Text PDFJ Transl Med
January 2025
Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Background: The sustained activation of androgen receptor splice variant-7 (AR-V7) is a key factor in the resistance of castration-resistant prostate cancer (CRPC) to second-generation anti-androgens such as enzalutamide (ENZ). The AR/AR-V7 protein is regulated by the E3 ubiquitin ligase STUB1 and a complex involving HSP70, but the precise mechanism remains unclear.
Methods: High-throughput RNA sequencing was used to identify differentially expressed circular RNAs (circRNAs) in ENZ-resistant and control CRPC cells.
BMC Cancer
January 2025
Department of Urology, Fujian Union Hospital, Fujian Medical University, Fuzhou, 350001, Fujian Province, China.
Background: Prostate cancer (PCa) is definitively diagnosed by systematic prostate biopsy (SBx) with 13 cores. This method, however, can increase the risk of urinary retention, infection and bleeding due to the excessive number of biopsy cores.
Methods: We retrospectively analyzed 622 patients who underwent SBx with prostate multiparametric MRI (mpMRI) from two centers between January 2014 to June 2022.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!