AI Article Synopsis
- The study explored how hematocrit levels and skin exposure affect the effectiveness of phototherapy for treating neonatal jaundice.
- Findings indicated that hematocrit levels do not impact the effectiveness of phototherapy, but the amount of skin exposed to light is crucial.
- Additionally, it was found that blue light does not sufficiently penetrate tissues like the brain or stomach to modify bilirubin pigment in postmortem cases.
Article Abstract
In order to investigate the main sites of action of phototherapy in the treatment of neonatal jaundice we studied (a) the in vivo and in vitro relationship between the hematocrit and the effectiveness of phototherapy, and (b) the effect of varying the skin area exposed to light. The results show that the hematocrit does not influence in vivo the efficacy of phototherapy, while they confirm that the total skin surface exposed to light is important in determining the effectiveness of light treatment. The authors have also studied the possible action of phototherapy on bilirubin solutions placed into the postmortem brain or the stomach. The results suggest that blue light does not penetrate strongly enough to photomodify the exposed pigment.
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| http://dx.doi.org/10.1159/000241630 | DOI Listing |
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