Ruberythric acid and alizarin glucuronide, the biologic secretion product obtained from the alizarin derivative, stop the crystallization of calcium oxalate and calcium phosphate in the physiologic milieu of the urine. This effect is thought to be due to a soluble alizarin glucuronide: calcium chelate (2:1 mol). From this finding, we deduce that the solubility of calcium oxalate and calcium phosphate in the urine of humans can be increased through the oral administration of oxianthraquinone.
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