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Antituberculosis properties of methyldioxotetrahydropyrimidine sulfonisonicotinoyl hydrazide (MSH) registered in Russia under the name of tubosan of the class of immunotropic agents were investigated with the use of 78 clinical isolates of Mycobacterium tuberculosis (MBT). In concentration of 60 or 80 mcg/ml the drug showed significant antituberculosis activity. The effect of MSH on drug susceptible MBT was bactericidal.
View Article and Find Full Text PDFClinico-roentgenologic and bacteriologic efficacy and safety of rifapex (rifapentin) were investigated in the complex therapy of 90 patients with newly recorded drug-susceptible tuberculosis. Pifapex was shown to be effective in the treatment of the patients during the acute phase of the disease, during the treatment completeness and during the short preoperative period.
View Article and Find Full Text PDFAntibacterial therapy is the most important component of the complex management of pyo-destructive forms of LRTI. Since the microbial flora is rather variable and polymorphous, antibiotics used in the treatment of LRTI should be active against both aerobic (especially gramnegative) and anaerobic pathogens. The aim of the study was to prove, on the basis of the bacteriological and clinical findings, the validity of the use of cefoperazone/sulbactam (CS), the only inhibitor-protected cephalosporin, for the monotherapy of patients with LRTI.
View Article and Find Full Text PDFThe diagnosis and therapy of 87 patients with sarcoidosis admitted to the Central Military Clinical Tubercular Hospital were analyzed. The diagnosis was based on the data of clinicoroentgenologic investigation and histologic examination of the specimen taken from the affected tissue. The differential diagnosis with tuberculosis is obligatory.
View Article and Find Full Text PDF[The classification of chronic pleurisy and the limits of its conservative treatment].
Lik Sprava
January 1997
The author focuses on the pathoanatomical and pathophysiological aspects of chronic pleuritis, ways of formation of chronic pulmonary heart. The clinico-roentgenologic classification proposed by the author suggests limits to the conservative treatment of pleuritis together with the indications for surgical intervention preventing the above complication. Using the criteria of the author's classification, there have been carried out a total of 211 surgical interventions; of these, 203 were pleurectomies.
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