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Allograft tolerance after adult living donor liver transplantation: a case-control study.
BMC Surg
January 2025
Department of Anesthesiology and Intensive Care and Pain Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Background: To investigate the incidence and potential predictors of immune tolerance among adult living donor liver transplant (LDLT) recipients.
Methods: This case-control study included adult recipients who underwent LDLT between May 2004 and January 2018, with at least a 5-year follow-up after LDLT. We divided the study recipients into two groups: Group 1 (Tolerance Group) included recipients who achieved operational or prope tolerance for at least one year; Group 2 (Control Group) included recipients who did not achieve tolerance.
Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening.
Sci Rep
January 2025
Molecular Biology and Stem Cell Research Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science & Technology, Chennai, Tamilnadu, India.
Model organisms are vital for biomedical research and drug testing but face high costs, complexity, and ethical issues. While newer techniques like organoids and assembloids have shown improvements, they still remain inadequate in addressing all research needs. In this study, we present a new method for maintaining the prostate gland of the earthworm, Eudrilus eugeniae ex vivo and examine its potential for regeneration and drug screening.
View Article and Find Full Text PDFPyrolytic conversion of construction, renovation, and demolition (CRD) wood wastes in Québec to biochar: Production, characterization, and identifying relevant stability indices for carbon sequestration.
Sci Total Environ
January 2025
Université du Québec à Trois-Rivières Trois-Rivieres, Quebec, Canada.
Management of heterogeneous construction, renovation, and demolition (CRD) wood residues in Québec brings into light, a widespread topic under discussion related to their current disposal methods in landfills, that may lead to environmental concerns. With rising forfeitures from a legal standpoint, alternative treatment methods for CRD wood wastes are being explored. Thermochemical biomass conversion techniques can be employed to depolymerize low-quality end-of-life CRD wood and valorize it to bio-based products.
View Article and Find Full Text PDFOptimizing Extraction Solvents for Plant Chemical Analysis Using H NMR and Principal Component Analysis.
Methods Mol Biol
January 2025
Natural Product Lab, Institute of Biology, Leiden University, Leiden, The Netherlands.
Natural products, particularly plants, remain a vital source of bioactive compounds owing to their unparalleled metabolic diversity across pharmaceuticals, cosmetics, foods, and agriculture. However, this diversity, encompassing not only a multitude of compounds but also their varying chemical and physical properties, presents a challenge in their effective utilization. Targeted analysis of specific metabolites, as well as untargeted approaches covering a wide metabolite range, necessitate optimal extraction solvents tailored to meet diverse requirements.
View Article and Find Full Text PDFMicroNIR spectroscopy with chemometric analysis provides rapid protein content evaluation and prediction of semi-refined flaxseed protein extract produced via pulsed electric field (PEF)-assisted extraction.
Food Chem
January 2025
Department of Food Science, University of Otago, Dunedin 9016, New Zealand; Riddet Institute, Private Bag 11 222, Palmerston North 4442, New Zealand.
Near-infrared (NIR) spectroscopy with chemometrics was used to evaluate semi-refined flaxseed protein extract (SRFPE) and predict its protein content. The effect of extraction medium (water vs. alkaline) employed after pulsed electric field (PEF) treatment on protein yield was also studied.
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