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Hydrogen Bonding Polarization Strengthening the Peptide-Based Hydrogels.
J Phys Chem B
December 2024
Research Institute of Interdisciplinary Science & School of Materials Science and Engineering, Dongguan University of Technology, Dongguan 523808, China.
Peptide-based hydrogels form a kind of promising material broadly used in biomedicine and biotechnology. However, the correlation between their hydrogen bonding dynamics and mechanical properties remains uncertain. In this study, we found that the adoption of β-sheet and α-helix secondary structures by ECF-5 and GFF-5 peptides, respectively, could further form fiber networks to immobilize water molecules into hydrogels.
View Article and Find Full Text PDFMetabolic profiling and antibacterial activity of tree wood extracts obtained under variable extraction conditions.
Metabolomics
December 2024
School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, B15 2TT, UK.
Introduction: Tree bacterial diseases are a threat in forestry due to their increasing incidence and severity. Understanding tree defence mechanisms requires evaluating metabolic changes arising during infection. Metabolite extraction affects the chemical diversity of the samples and, therefore, the biological relevance of the data.
View Article and Find Full Text PDFDevelopment and Evaluation of Non-Antibiotic Growth Promoters for Food Animals.
Vet Sci
December 2024
National Reference Laboratory of Veterinary Drug Residues (HZAU), Veterinary Medicine Research Center, Huazhong Agricultural University, Wuhan 430070, China.
The widespread utilization of antibiotic growth promoters (AGPs) boosts the growth rate of food animals and enhances human living standards. Nevertheless, it is accompanied by escalating antibiotic resistance. Consequently, there is an urgent demand to develop novel alternatives to growth promoters.
View Article and Find Full Text PDF"Head-to-Toe" Lipid Properties Govern the Binding and Cargo Transfer of High-Density Lipoprotein.
Membranes (Basel)
December 2024
Department of Medical Engineering, Upper Austria University of Applied Sciences, 4020 Linz, Austria.
The viscoelastic properties of biological membranes are crucial in controlling cellular functions and are determined primarily by the lipids' composition and structure. This work studies these properties by varying the structure of the constituting lipids in order to influence their interaction with high-density lipoprotein (HDL) particles. Various fluorescence-based techniques were applied to study lipid domains, membrane order, and the overall lateral as well as the molecule-internal glycerol region mobility in HDL-membrane interactions (i.
View Article and Find Full Text PDFThe Langmuir Monolayer as a Model Membrane System for Studying the Interactions of Poly(Butyl Cyanoacrylate) Nanoparticles with Phospholipids at the Air/Water Interface.
Membranes (Basel)
December 2024
Department of Physical Chemistry, Faculty of Chemistry and Pharmacy, Sofia University St. Kliment Ohridski, 1 "James Bourchier" Blvd., 1164 Sofia, Bulgaria.
Poly(butyl cyanoacrylate) (PBCA) nanoparticles have numerous applications, including drug and gene delivery, molecular imaging, and cancer therapy. To uncover the molecular mechanisms underlying their interactions with cell membranes, we utilized a Langmuir monolayer as a model membrane system. This approach enabled us to investigate the processes of penetration and reorganization of PBCA nanoparticles when deposited in a phospholipid monolayer subphase.
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