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Diagnostic Blind Spot: Physicians Overlook Atrial Fibrillation in Pacemaker-Dependent Patients.
Pacing Clin Electrophysiol
January 2025
Department of Cardiology, Lady Davis Carmel Medical Center, Haifa, Israel.
Background: Pacemaker recipients demonstrate a higher prevalence of atrial fibrillation (AF), yet the regular ventricular activation in pacemaker-dependent patients with AF presents a substantial diagnostic challenge.
Methods: A total of 310 medical practitioners completed a brief, validated survey consisting of three electrocardiograms displaying AF with ventricular pacing. Participants were instructed to identify the underlying rhythm.
Four cardiomyopathy patients with a heterozygous DSG2 p.Arg119Ter variant.
Hum Genome Var
December 2024
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.
DSG2, encoding desmoglein-2, is one of the causative genes of arrhythmogenic cardiomyopathy. We previously identified a homozygous DSG2 p.Arg119Ter stop-gain variant in a patient with juvenile-onset cardiomyopathy and advanced biventricular heart failure.
View Article and Find Full Text PDFConcealed cardiomyopathy as an emerging cause of sudden cardiac arrest and sudden cardiac death.
Nat Cardiovasc Res
November 2024
Faculty of Medicine and Heath, the University of Sydney, Sydney, New South Wales, Australia.
Article Synopsis
- Inherited cardiomyopathies can present differently in patients, with some showing no symptoms while others may experience sudden cardiac death at a young age.
- Traditionally, the risk of life-threatening heart issues has been linked to visible structural heart problems, but genetic testing has revealed cases where this risk exists even without obvious symptoms.
- Growing awareness and understanding of concealed cardiomyopathy, including its genetic causes and arrhythmia mechanisms, is crucial for better management and support for affected families.
A change in QT interval and ST-segment after radiofrequency catheter ablation in pediatric patients with Wolff-Parkinson-White syndrome.
J Electrocardiol
December 2024
Department of Pediatrics, Toyama Prefectural Central Hospital, Toyama, Japan.
Article Synopsis
- A study on pediatric patients with Wolff-Parkinson-White (WPW) syndrome examined how radiofrequency catheter ablation (RFA) affects QT, JT intervals, and ST-segment changes.
- Out of 27 patients, those with ventricular preexcitation (manifest group) had a notably longer QT interval before RFA compared to those without it (concealed group), and their QT interval significantly shortened after the procedure.
- Although transient ST-segment changes and abnormalities were common in the manifest group post-RFA, most ECG changes normalized within one month.
Analysis of the therapeutic effect of right mid-axillary approach in the surgical treatment of ASD and VSD in children.
J Cardiothorac Surg
October 2024
Department of Cardiac Vascular Surgery, Yan An Hospital of Kunming City, Kunming, 65000, Yunnan, China.
Background: To compare the therapeutic effects of right vertical infra-axillary thoracotomy (RVIAT) and Standard Median Sternotomy (SMS) in the repair of atrial septal defect (ASD) and ventricular septal defect (VSD), and to evaluate the safety and effectiveness of right subaxillary incision technique in the surgical treatment of common congenital heart disease (CHD) in children.
Methods: Data of children diagnosed with ASD repair or VSD repair at our center from September 2019 to September 2022 were collected. Based on propensity score matching, 214 children (107 in the RVIAT group and 107 in the SMS group) who completed ASD repair surgery and 242 children (121 in the RVIAT group and 121 in the SMS group) who completed VSD repair surgery were selected for the study.
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