Fourteen patients suffering from actinic prurigo were treated with thalidomide. Eleven patients showed lasting improvement on the drug and three of these remained symptom-free after discontinuing therapy. No major side-effects were observed. Thalidomide is an effective drug in the treatment of actinic prurigo but it must be used with adequate contraception in women of child-bearing age.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2133.1983.tb04601.xDOI Listing

Publication Analysis

Top Keywords

actinic prurigo
12
thalidomide actinic
4
prurigo fourteen
4
fourteen patients
4
patients suffering
4
suffering actinic
4
prurigo treated
4
treated thalidomide
4
thalidomide eleven
4
eleven patients
4

Similar Publications

Exploring adult-onset actinic prurigo in Thailand.

Dermatol Reports

September 2024

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Article Synopsis
  • Actinic prurigo (AP)
  • is a rare skin condition primarily affecting adults in Thailand, with a mean onset age of 45.5 years, and is more common in males (66.7%) compared to females.
  • Clinical features
  • include papules mostly on the face and upper extremities, with some patients experiencing mucositis; phototesting showed varying sensitivity to UVA and UVB light.
  • Treatment outcomes
  • indicate that 60% of patients received systemic immunosuppressants; while the median time for clinical improvement was about 8.6 months, only a small number achieved complete remission.
View Article and Find Full Text PDF
Article Synopsis
  • - Actinic prurigo is a rare skin condition that causes itchy, raised lesions and is particularly difficult to treat, especially in children.
  • - Effective management requires strict sun protection, as symptoms can last for most of the year.
  • - A case study of an 8-year-old patient showed quick improvement of symptoms using baricitinib, a medication not commonly used for this condition.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!