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Single and multitarget stereotactic radiosurgery (SRS) with single isocenter in the treatment of multiple brain metastases (BM): institutional experience.
Clin Transl Oncol
January 2025
Department of Radiation Oncology, HM Hospitales, Madrid, Spain.
Introduction: SRS for the treatment of limited brain metastases (BM) is widely accepted, but there are still limitations in the management of numerous BM. Frameless single-isocenter multitarget SRS is a novel technique that allows for rapid treatment delivery to multiple BM. We report our preliminary clinical, dosimetric, and patient´s shifts outcomes with this technique.
View Article and Find Full Text PDFEffects of axillary dose restriction on plan quality and acute radiation dermatitis in breast cancer radiotherapy.
Med Dosim
January 2025
Department of Radiation Oncology, People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences, 530021, Nanning, Guangxi, China. Electronic address:
Axillary dose restriction (ADR) is rarely implemented in breast cancer radiotherapy by radiation oncologists to minimize exposure to organs at risk (OARs), particularly the axilla. This prospective randomized controlled study aims to evaluate the efficacy of ADR in improving plan quality (PQ) and its impact on acute radiation dermatitis (ARD) in breast cancer radiotherapy. The study recruited breast cancer patients who required postoperative radiotherapy but did not have an indication for axillary irradiation.
View Article and Find Full Text PDFDosimetric impact of arc simulation angular resolution in single-isocentre multi-target stereotactic radiosurgery.
Radiol Phys Technol
January 2025
Department of Radiotherapy, Sri Shankara Cancer Hospital and Research Centre, 1st Cross, Shankarapuram, Basavanagui, Bengaluru, 560004, Karnataka, India.
This study evaluates the dosimetric impact of arc simulation angular resolution in VMAT-based Single Isocentre Multiple Target (SIMT) SRS, focusing on their dependence on target size, isocentre distance, number of arcs, and arc type. A phantom study analysed angular resolution (0.5°, 1°, 2°) effects on dosimetric accuracy for PTVs of 0.
View Article and Find Full Text PDFComparison between flattening filter and flattening filter-free photon beams in head and neck cancer patients using volumetric modulated arc therapy technique.
Radiat Environ Biophys
January 2025
Radiation Physics, Faculty of Science, Al -Azhar University, Cairo, Egypt.
This study aimed to evaluate the dosimetric and clinical outcomes of flattening filter (FF) versus flattening filter-free (FFF) beams in head and neck cancer (HNC) patients treated with volumetric modulated arc therapy (VMAT). Twenty-four patients with 70/59.4/54 Gy dose prescribed in 33 fractions with simultaneous integrated boost treatment were retrospectively analyzed to compare treatment delivery efficiency, target coverage, sparing of organs at risk (OARs), and remaining volume at risk (RVR) in two HNC groups (nasopharyngeal and oropharyngeal).
View Article and Find Full Text PDFEffect of Prepectoral Versus Subpectoral Implant-Based Reconstruction on Post-Mastectomy Radiation Dosimetry.
Ann Surg Oncol
January 2025
Section of Plastic and Reconstructive Surgery, Department of Surgery, University of Michigan Health Systems, Ann Arbor, MI, USA.
Background: The placement of breast implants in a prepectoral plane has become increasingly popular in breast reconstruction, although data on how this affects radiation delivery in women with breast cancer are limited. This study aimed to assess the dosimetric differences in radiation plans for immediate breast reconstruction between prepectoral and subpectoral implants.
Methods: In this study, a retrospective review and dosimetric analysis of patients with breast cancer who underwent immediate implant-based reconstruction and postmastectomy radiation therapy (PMRT) were performed.
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