Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
First branchial cleft anomalies in children: long-term outcome in 16 patients.
Eur Arch Otorhinolaryngol
January 2025
Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.
Introduction: First branchial cleft anomalies (FBCA) are rare congenital head and neck malformations, often subject to incorrect diagnosis and treatment. We present our experience with FBCA, focusing on clinical presentation, diagnosis, perioperative relation to the facial nerve, surgical approach, complications and patient satisfaction.
Methods: A consecutive cohort of 16 patients undergoing surgical treatment for FBCA between 1999 and 2021 was analyzed.
[The connection between back pain and obesity].
Orthopadie (Heidelb)
January 2025
Klinik für Orthopädie, Unfall- und Handchirurgie, HELIOS Klinikum Krefeld, Lutherplatz 40, 47805, Krefeld, Deutschland.
Background: Obesity is increasingly being recognized as a significant risk factor for the development and worsening of back pain. In order to make possible adjustments to therapies and lifestyle, the relationship must first be understood.
Method: This article attempts to explain the relationship between obesity and back pain based on the existing literature.
Replication across O6-methylguanine activates futile cycling of DNA mismatch repair attempts assisted by the chromatin remodeling enzyme Smarcad1.
J Biochem
January 2025
Faculty of Science, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
SN1-type alkylating reagents generate O6-methylguanine (meG) lesions that activate the mismatch repair (MMR) response. Since post-replicative MMR specifically targets the nascent strand, meG on the template strand is refractory to rectification by MMR and, therefore, can induce non-productive MMR reactions. The cycling of futile MMR attempts is proposed to cause DNA double-strand breaks in the subsequent S phase, leading to ATR-checkpoint-mediated G2 arrest and apoptosis.
View Article and Find Full Text PDFMicrobiome metabolic capacity is buffered against phylotype losses by functional redundancy.
Appl Environ Microbiol
January 2025
Department of Microbiology, Ohio State University, Columbus, Ohio, USA.
Unlabelled: Many animals contain a species-rich and diverse gut microbiota that likely contributes to several host-supportive services that include diet processing and nutrient provisioning. Loss of microbiome taxa and their associated metabolic functions as result of perturbations may result in loss of microbiome-level services and reduction of metabolic capacity. If metabolic functions are shared by multiple taxa (i.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!