Twelve out of 32 neurosecretory neurons in the paraventricular nucleus of rats showed a silent phase following subthreshold stimulation to the posterior pituitary gland. After suprathreshold stimulation, the duration of the silent phase was significantly longer than that of the remaining 20 neurons, which did not show the silent phase at subthreshold stimulation. The latency and threshold in the former neurons were significantly longer and higher than those of the latter neurons. These data indicate a relationship between the recurrent inhibitory system and other electrical properties in the paraventricular neurons.

Download full-text PDF

Source
http://dx.doi.org/10.1016/0006-8993(83)90479-1DOI Listing

Publication Analysis

Top Keywords

silent phase
12
electrical properties
8
properties paraventricular
8
neurosecretory neurons
8
phase subthreshold
8
subthreshold stimulation
8
neurons
6
paraventricular neurosecretory
4
neurons recurrent
4
recurrent inhibition
4

Similar Publications

Background: The crucial steps in beta cell stimulus-secretion coupling upon stimulation with glucose are oscillatory changes in metabolism, membrane potential, intracellular calcium concentration, and exocytosis. The changes in membrane potential consist of bursts of spikes, with silent phases between them being dominated by membrane repolarization and absence of spikes. Assessing intra- and intercellular coupling at the multicellular level is possible with ever-increasing detail, but our current ability to simultaneously resolve spikes from many beta cells remains limited to double-impalement electrophysiological recordings.

View Article and Find Full Text PDF

Osteoporosis Knowledge Assessment Tool - Tamil (OKAT-T) in postmenopausal women: A validity and reliability study.

J Clin Orthop Trauma

January 2025

Resident, Department of Community Medicine, Mahatma Gandhi Medical College and Research Institute, SBVU (Deemed to be University), Pondicherry, India.

Introduction: Osteoporosis is a silent disease that is more prevalent among postmenopausal women (PMW) due to hormonal transition. Various toolkits, including the Osteoporosis Knowledge Assessment Tool (OKAT), were available for the knowledge assessment. The Osteoporosis-related knowledge is crucial for preventing osteoporosis, but there is no validated, reliable questionnaire in Tamil to measure this knowledge.

View Article and Find Full Text PDF

Pediatric case of hemoglobin I-high Wycombe variant.

Clin Chim Acta

December 2024

Department of Pathology & Immunology, Baylor College of Medicine, USA; Department of Pathology, Texas Children's Hospital, Houston, TX, USA. Electronic address:

Over 1400 variants of hemoglobin (Hb) have been identified and characterized with phenotypes ranging from clinically silent to severe clinical manifestations in carriers. Different analytical methods have been established to detect Hb variants. Here, we report the first pediatric case of hemoglobin I-High Wycombe [β59(E3) Lys → Glu] variant found in an infant of Mexican-American descent.

View Article and Find Full Text PDF

Introduction: The safety and efficacy of paroxysmal atrial fibrillation (PAF) ablation with the HELIOSTAR multielectrode radiofrequency (RF) balloon catheter have been demonstrated in European studies; data from elsewhere are lacking. This prospective, multicenter study conducted in the United States, Italy, and China investigated the safety and efficacy of pulmonary vein isolation (PVI) using HELIOSTAR in drug-refractory symptomatic PAF.

Methods: The primary effectiveness endpoint (PEE) was 12-month freedom from documented atrial fibrillation/atrial flutter/atrial tachycardia plus freedom from acute procedural failure, nonstudy catheter failure, repeat ablation failure, direct current cardioversion (DCCV), and Class I/III antiarrhythmic drug (AAD) failure.

View Article and Find Full Text PDF

Purpose: Patient experiences of brachytherapy for locally advanced cervical cancer (LACC) are widely variable, with reports of difficult and traumatic experiences and aspects of care requiring improvement. The aim of this study was to develop patient care recommendations and consult with key stakeholders to review, refine and prioritise recommendations.

Methods: Phase 1: Patient care recommendations were developed from qualitative exploratory study data.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!