Comparative epidemiological study in population of patients with schizophrenia in one of the Moscow regions revealed differential morbidity risk in posterity. Convincing proofs obtained showed sick children with schizophrenia prevalence in sick mothers, but not fathers' posterity. Such a conclusion on the representative populational material was made for the first time. The study showed the specificity of differential morbidity risk in control groups of patients with other disease entities analyzed. Different factors significance in so-called "maternal effect" manifestation are discussed.

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