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Cutaneous metastases from rectal adenocarcinoma: A case report.
SAGE Open Med Case Rep
December 2024
Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Cutaneous metastases from colorectal cancer are an uncommon but critical finding, typically signaling advanced disease with poor prognosis. This case report describes a 64-year-old woman with a limited past medical history who presented to our outpatient dermatology practice with rapidly spreading erythematous, indurated, and nearly verruciform plaques in the groin, vaginal, and perineal region. Biopsy confirmed metastatic adenocarcinoma of colonic origin, and diagnostic imaging, and colonoscopy revealed stage IV colorectal cancer involving extensive cutaneous, lymphatic, and visceral metastases.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses a rare case of verruciform xanthoma of the penis in a male patient who also has genital lichen sclerosus.
- This is only the second documented case of this particular condition.
- The authors recommend that when diagnosing verruciform xanthoma, healthcare providers should closely check for signs of lichen sclerosus, as these signs can be subtle.
Human Papillomavirus-Associated Giant Clear Cell Acanthoma and Squamous Cell Carcinoma: A Rare Case Report and Literature Review.
J Clin Med
April 2024
Department of Plastic Surgery, Peninsula Health, Melbourne, VIC 3199, Australia.
Article Synopsis
- - Clear cell acanthoma (CCA) is a rare, benign skin growth often not linked to HPV, while squamous cell carcinoma (SCC) is a more aggressive skin cancer associated with UV exposure and HPV.
- - A case involving a 64-year-old man found CCA and keratinized SCC in the same lesion, highlighting the complexity of diagnosing and treating these conditions together.
- - Limited research suggests a connection between HPV and CCA, necessitating further study to better understand their relationship and improve treatment approaches for patients with both conditions.
Oral verruciform xanthomas mimicking potentially malignant disorders.
J Clin Exp Dent
April 2024
DDS, MSc, PhD. Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Article Synopsis
- Verruciform xanthoma is a rare reactive lesion that typically appears in the skin but can also occur in the oral cavity, where it may be mistaken for leukoplakia.
- The text describes two cases of 30-year-old individuals with white plaques on the tongue and floor of the mouth, which were confirmed to be oral verruciform xanthomas through histopathological analysis.
- It's important for dental professionals to consider verruciform xanthoma in their differential diagnosis for potential oral cancer since it can appear in high-risk areas, with histopathological analysis being the most reliable method for diagnosis.
A Case of Verruciform Xanthoma of Labia in a Child.
Clin Cosmet Investig Dermatol
April 2024
Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi, People's Republic of China.
Article Synopsis
- - The study presents a case of verruciform xanthoma (VX), a rare and benign skin condition, found in a 12-year-old female with vulvar lesions lasting over a decade without discomfort.
- - Examination revealed red, lobulated patches and specific histopathological features, including abnormal keratinization and inflammatory cell infiltration, leading to the diagnosis of VX.
- - Surgical treatment resulted in a successful outcome, highlighting an effective approach for managing this condition.
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