It is found that changes induced by moderate hypothermia (30 degrees C) in the brain tissue glutaminase activity and its temperature dependence are not removed after self-heating up to the body temperature of 37 degrees C. Self-heating after deep hypothermia (20 degrees C) causes a considerable increase in the brain tissues glutaminase activity at all studied incubation temperatures (37, 30, 20 and 10 degrees C) as compared to control rats and rats under hypothermia. The increase in the brain tissue glutaminase activity during self-heating of cooled animals may be considered as a compensatory reaction under conditions of a higher utilization of glutamate by the brain.

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