Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Deep Learning-Powered CT-Less Multitracer Organ Segmentation From PET Images: A Solution for Unreliable CT Segmentation in PET/CT Imaging.
Clin Nucl Med
January 2025
From the Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland.
Purpose: The common approach for organ segmentation in hybrid imaging relies on coregistered CT (CTAC) images. This method, however, presents several limitations in real clinical workflows where mismatch between PET and CT images are very common. Moreover, low-dose CTAC images have poor quality, thus challenging the segmentation task.
View Article and Find Full Text PDFStandardization of Subcutaneous Injection of Prefilled Anticoagulants Through Lean Six Sigma Management: A Before-After Study.
J Craniofac Surg
January 2025
Department of Neurosurgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences.
Aim: The aim of this study was to investigate the impact of the Lean Six Sigma management approach on the standardization of nurses' prefilled anticoagulant subcutaneous injection practices, with a focus on improving anticoagulation outcomes, reducing patient complications, and enhancing overall patient satisfaction.
Background: The lack of standards for prefilled anticoagulant injection has resulted in a high complication rate, decreased patient satisfaction, and diminished service quality. This study investigated the impact of the Lean Six Sigma management approach on the standardization of nurses' prefilled anticoagulant subcutaneous injection practices.
Magnetic Field-Accelerated Nonthermal Plasma Digestion for Field Pretreatment and Determination of Heavy Metals in Biological Samples.
Anal Chem
January 2025
Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China.
Field analysis of heavy metals in biological samples is essential for assessing their potential threats to human health. The development of portable pretreatment and detection devices is crucial to address this challenge. Herein, a magnetic field-accelerated nonthermal plasma digestion device using dielectric barrier discharge (DBD) is designed for the rapid and environmentally friendly pretreatment of biological samples and subsequently combined with point discharge-optical emission spectrometry (PD-OES) for sensitive determination of heavy metals.
View Article and Find Full Text PDFOutpatient parenteral antibiotic therapy with elastomeric pumps, what is the flowrate accuracy?
J Vasc Access
January 2025
EXPLOR! Center, Air Liquide Healthcare, Bagneux, France.
Background: Outpatient Parenteral Antibiotic Therapy (OPAT) services have expanded throughout the world thanks to elastomeric pumps (EP). Their flowrate is known to vary by ±15%. Treatment effectiveness and the organization of care at home may be impacted, especially with piperacillin/tazobactam infusion (TAZ).
View Article and Find Full Text PDFObservation of Ɛ-AlKeggin-Oligonucleotide Complexes in Analytical Sample Solutions.
J Pharm Sci
January 2025
Ionis Pharmaceuticals, Inc., 2855 Gazelle Ct., Carlsbad, CA 92010. Electronic address:
Complexes formed between aluminum cluster molecules that adopt a Ɛ-Al-Keggin structure and antisense oligonucleotides were observed as new impurity peaks during drug product stability testing. The Ɛ-Al-Keggin molecules were determined to be artifacts of the analysis, originating from contact between antisense oligonucleotide drug product solution and aluminum weigh boats used to prepare the analytical sample solutions The presence of the Ɛ-Al-Keggin molecules was confirmed through synthesis of the Keggin molecule through an established route and subsequent spiking studies. Binding affinity studies revealed that the Ɛ-Al-Keggin bound to oligonucleotide sequences of various lengths (10 to 20 bases) and base compositions, though there is some evidence for preferential binding to 5-methylcytosine-containing sequences.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!