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Pre-operative high-frequency ultrasound: a reliable management tool in auricular and nasal non-melanoma skin cancer.
J Dtsch Dermatol Ges
March 2024
Clinic of Dermatology and Allergology, University Clinic Ulm, Ulm, Germany.
Background And Objectives: The knowledge of depth infiltration in non-melanoma skin cancer (NMSC) using pre-operative ultrasound could enable clinicians to choose the most adequate therapeutic approach, avoiding unnecessary surgeries and expensive imaging methods, delaying diagnosis and treatment. Our single-center retrospective study determined the usefulness of high-frequency ultrasound (HFUS) for depth infiltration assessment in auricular and nasal NMSC and assessed the subsequent change in therapeutic approach.
Patients And Methods: In 60 NMSC cases, we assessed the accuracy of HFUS in cartilaginous/bone infiltration detection as well as the correlation of sonographic and histological parameters.
An Italian nationwide survey on the evolution of autoantibody diagnostics in autoimmune rheumatic diseases.
Clin Exp Rheumatol
November 2023
Laboratorio di Patologia Clinica, Ospedale San Antonio, Azienda Sanitaria Universitaria Integrata di Udine, Italy.
Article Synopsis
- The Italian Society of Clinical Pathology and Laboratory Medicine conducted a nationwide survey to evaluate the adoption of new autoimmune diagnostic technologies and practices among autoimmunology laboratories in Italy.
- A questionnaire featuring 59 questions was distributed to 152 laboratories, assessing factors like test volume, technology used, automation level, testing methods, and interaction with clinicians.
- Results showed a high response rate (79.6%) with most labs using various advanced testing technologies and 65% providing interpretative comments in reports, suggesting a trend towards enhanced testing capabilities and closer collaboration with healthcare providers.
Effect of uterine torsion intrapartum on concentrations of placental estrogens and progesterone in cattle.
Vet Med Sci
July 2023
Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals with Ambulatory Service, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany.
Objective: The current study investigates how uterine torsion influences placental oestrogens and progesterone blood concentrations in intrapartum cows. Our research tests the hypothesis that intrapartum uterine torsion impairs the ability of the placenta to synthesize steroids and may also suppress the release of synthesized steroids into the maternal circulation.
Methods: The study included a total number of 37 intrapartum dairy cows of various breeds and ages.
Comparison of three progesterone quantification methods using blood samples drawn from bitches during the periovulatory phase.
Vet World
January 2022
Clinic for Obstetrics, Gynaecology and Andrology of Large and Small Animals with Veterinary Ambulance, Justus Liebig University, Giessen, Germany.
Background And Aim: Measuring blood progesterone (P4) concentration has become an essential diagnostic tool in small animal reproductive medicine. Methods enabling precise and rapid on-site measurements are in high demand, especially for the optimization of breeding management in bitches. This study aimed to compare two commercial on-site methods (Speed™ P4, Virbac [M1] and mini VIDAS®, bioMérieux [M2]) and a well-established radioimmunoassay (RIA), which was used as a reference method.
View Article and Find Full Text PDF[Precision intra-assay study in the absence of internal quality control: example of radioimmunoassay of procollagen III peptide].
Ann Biol Clin (Paris)
February 2022
Laboratoire de biochimie, DMU biologie et génomique médicales, AP-HP Sorbonne Université, Hôpital Saint-Antoine, Paris.
The first step to complete in a method validation of a biological analysis is the study of precision intra-assay. In the absence or insufficient quantity of control material, this study may be difficult to perform. This article proposes a methodology for preparing its own control samples for the radioimmunological assay of the amino-terminal peptide of procollagene type III (PIIIP).
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