While generally justifying the large amount of money invested in the treatment effort, evaluation studies of treatment centers for drug addiction do not offer a rational method of allocating scarce resources among the various available treatment programs. The problem is further confounded by different costs associated with the different programs and also because clients rarely complete the prescribed treatment. We developed functional relationships between treatment outcomes and time in treatment that allow the inclusion of probable length of stay of patients and cost per week for a particular treatment program in the evaluation considerations. The model evolved from a drug addiction treatment system operating in Newark, New Jersey consisting of six different treatment centres. Treatment outcome measures are derived from a psychosocial questionnaire which was administered to patients at appropriate time intervals. The questionnaire probed into the important facets of human behavior as related to the use or non-use of drugs for non-medical reasons. Gompertz curves reflecting treatment benefit are computed for each treatment center by least square fit of the collected data to appropriate differential equations and used together with cost of treatment and treatment retention rates to compute expected net benefit for each treatment center. These enable the researcher to find the treatment centers with the best treatment outcome or alternately with the best expected cost benefit ratio for any patient type.
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http://dx.doi.org/10.1016/0277-9536(82)90260-x | DOI Listing |
J Surg Res
January 2025
Department of Surgery, Washington University School of Medicine, Saint Louis, Missouri.
Background: Radioactive iodine (RAI) is a common treatment for various thyroid diseases. Previous studies have suggested susceptibility of parathyroid glands to the mutagenic effect of RAI and the development of primary hyperparathyroidism (PHPT). We tested the possible link between prior RAI treatment, disease presentation, and treatment outcomes.
View Article and Find Full Text PDFIntroduction: Solitary plasmacytomas are tumors characterized by a local increase of malignant plasma cells in soft tissue or bone and may occur anywhere without evidence of systemic disease. The aim was to focus on the main surgical techniques and outcomes for this rare chest wall tumor.
Methods: Patients with solitary plasmacytoma involving a rib, who were operated for diagnostic or treatment purposes between 2018 and 2023 were retrospectively reviewed.
J Pediatr Nurs
January 2025
Faculty of Nursing, Yarmouk University, Irbid, Jordan. Electronic address:
Background: Type 1 diabetes is the most common endocrine health condition among youth. Healthcare professionals must consider evidence-based guidelines in managing children and adolescents with diabetic ketoacidosis (DKA). The current study aims to assess the outcomes of implementing clinical guidelines by the American Diabetes Association to manage DKA among pediatrics in an emergency department in Palestine.
View Article and Find Full Text PDFCancer Treat Rev
January 2025
Department of Oncology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden. Electronic address:
Importance: Endocrine treatments, such as Tamoxifen (TAM) and/or Aromatase inhibitors (AI), are the adjuvant therapy of choice for hormone-receptor positive breast cancer. These agents are associated with menopausal symptoms, adversely affecting drug compliance. Topical estrogen (TE) has been proposed for symptom management, given its' local application and presumed reduced bioavailability, however its oncological safety remains uncertain.
View Article and Find Full Text PDFPlant Physiol Biochem
December 2024
College of Ecology and Environment, Chengdu University of Technology, Sichuan, 610059, China; Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, Lanzhou University, Lanzhou, 730000, China; Key Laboratory of Monitoring for Heavy Metal Pollutants, Ministry of Ecology and Environment, Hunan, 410019, China. Electronic address:
With the intensification of climate change coupled with the inadequate agricultural management in certain regions, plants face numerous challenges due to various abiotic stresses. Stress associated proteins (SAPs) are essential functional genes in plants for coping with stress. This research provides a functional analysis of OsSAP17, a protein belonging to the SAP family in rice.
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