[Effect of thyroliberin on the prolactin and thyrotropic and somatotropic hormone content of the blood plasma in insulin-dependent diabetes mellitus].

Twelve men, aged 17 to 43 years, with insulin-depending diabetes mellitus were examined during the decompensation stage. The patients were divided into 2 groups, depending on the disease duration. The stage of the hypothalamic-hypophyseal system was evaluated according to the blood plasma STH, TTH and prolactin levels and after intravenous injection of the Soviet thyroliberin (TRH). A significant increase in the basal prolactin level is seen in the group of patients with prolonged insulin-depending diabetes during the decompensation stage. The blood plasma STH content rises in this group of patients after intravenous STH injection. The data obtained testify that the changes in somatotropic and prolactotropic hypophyseal functions occur in the patients with prolonged insulin-depending diabetes mellitus within the decompensation stage.