Endodontic root filling following pulpectomy in Baboons was shown to induce diphasic consequences at the level of the periodontal ligament according to the time of the observation. Initially the specific activity of previously incorporated 3H Glycine decreased and the weight of extractible ligament increased at the same time. Later on, the turnover slowed down and, unexpectedly, the weight of the extractible ligament decreased. This could be explained since the periodotal ligament was shown to exhibit a transient inflammatory reaction followed initially by a tissue accretion and progressively by a partial amputation of the ligament volume compensated by an excess of bone deposit on the surface of the alveolar bone socket.

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