The combined effect of ethonium and 5 antibiotics belonging to different groups was studied with 30 clinical strains of P. aeruginosa. A 2--8-fold increase in the activity of kanamycin and tetracycline against some strains was observed. The MIC of carbenicillin, polymycin M and cefotaxime was lowered by 2--6 times and with respect to some strains by 16--32 times. The detergent is recommended to be used in combination with some antibiotics in treatment of infections caused by resistant strains of P. aeruginosa.
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