The 11th documented concurrence of anorexia nervosa (AN) and XO-gonadal dysgenesis (GD) is reported. This is the first endocrine study of such a disease combination. The patient, a 15-year-old girl, has been followed since early childhood and comprehensive endocrinological investigation were performed before, during and after the episode of AN. The dynamic changes in the thyroid and pituitary hormones were in concordance with those already observed by us as well as by others in patients with AN. The most remarkable observations concerned the gonadotrophin secretion: during the anorectic episode basal levels and peak responses to LRH and both LH and FSH were seen to decrease from the hypergonadotrophic range to the normal prepubertal range whereas after recovery from AN and regain of weight these rose back to castration levels. AN would seem to be the only condition yet known able to abolish temporarily the hypergonadotrophic state of GD, a fact favouring the hypothesis that AN is associated with a reversible hypothalamic dysfunction. It is assumed that this disturbance is due to nutritional as well as to psychological factors. The significance of the coexistence of AN and GD is discussed and it is suggested that psychological factors in GD may be implicated in this association.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1530/acta.0.1000363 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Translation and Adaptation of the SCOFF Questionnaire to the Greek Language (G-SCOFF) Using a Tertiary-Setting Adolescent Sample.
Nutrients
January 2025
Department of Nutrition, General Hospital of Thessaloniki "G. Gennimatas", 41 Ethnikis Aminis Str., GR-54635 Thessaloniki, Greece.
Background/objectives: Feeding and eating disorders (FEDs) constitute an important mental health problem today, especially among youngsters. The Sick, Control, One, Fat, Food (SCOFF) questionnaire was developed 25 years ago and remains the most frequently applied screening tool for FEDs among adults and youngsters. The aim of the present study was to translate and adapt the SCOFF questionnaire to the Greek language, using a tertiary-setting adolescent sample.
View Article and Find Full Text PDFRelative Energy Deficiency in Sport-Multidisciplinary Treatment in Clinical Practice.
Nutrients
January 2025
Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, 72076 Tübingen, Germany.
Background/objectives: The primary aim of this study was to characterize athletes approaching an outpatient interdisciplinary and multidisciplinary consultation structure for athletes with a suspected relative energy deficiency in sport (REDs) cross-sectionally and longitudinally to prove treatment efficacy.
Methods: Data of 58 athletes suspected of REDs were collected at the onset (t) and completion (t) of interdisciplinary and multidisciplinary REDs treatment (clinical practice) between January 2019 and December 2022. The data included extracted information from medical records, anthropometric characteristics, physical performance diagnostics, laboratory values, dietary records, and partially gynecological and psychosomatic diagnostics.
The Neural Correlates of Body Image Processing in Anorexia Nervosa and Bulimia Nervosa: An Activation Likelihood Estimation Meta-Analysis of fMRI Studies.
Int J Environ Res Public Health
January 2025
School of Psychology, Bond University, Gold Coast, QLD 4226, Australia.
Body image concerns are key prognostic and pathogenic factors of anorexia nervosa (AN) and bulimia nervosa (BN). This study aimed to investigate the neural mechanisms underlying body image perception across its two domains of estimation and satisfaction in anorexia and bulimia patients and healthy controls (HC). Systematic searches were conducted across eight databases, including PubMed; Cochrane Library; Ovid; Google Scholar; Sage Journals; Scopus; PsycInfo; and ScienceDirect, from database inception until the 23rd of April 2023.
View Article and Find Full Text PDFThe brainstem reticular formation pivots abnormal neural transmission in the course of Anorexia Nervosa.
J Neural Transm (Vienna)
January 2025
Human Anatomy, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma 55, Pisa, 56100, PI, Italy.
Anorexia nervosa (AN) represents an eating disorder, which features the highest rate of mortality among all psychiatric disorders. The disease prevalence is increasing steadily, and an effective cure is missing. The neurobiology of the disease is largely unknown, and only a few studies were designed to disclose specific brain areas, where altered neural transmission may occur.
View Article and Find Full Text PDFBackground: Anorexia nervosa has the highest mortality rate of any psychiatric disorder, and purging behaviors can cause a fatal electrolyte and acid-base imbalance. Routine laboratory testing during inpatient care is essential because these patients often provide inaccurate information about their diet and purging behaviors. However, blood gas analysis for an acid-base evaluation is rarely performed in the psychiatric setting because psychiatrists are not accustomed to evaluating the results.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!