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Bending the curve of biodiversity loss requires a 'satnav' for nature.
Philos Trans R Soc Lond B Biol Sci
January 2025
Biodiversity Futures Lab, Natural History Museum, London SW7 5BD, UK.
Georgina Mace proposed bending the curve of biodiversity loss as a fitting ambition for the Convention on Biological Diversity. The new Global Biodiversity Monitoring Framework (GBMF) may increase the chances of meeting the goals and targets in the Kunming-Montreal Global Biodiversity Framework (KMGBF), which requires bending the curve. To meet the outcome goals of KMGBF, the GBMF should support adaptive policy responses to the state of biodiversity, which in turn requires a 'satnav' for nature.
View Article and Find Full Text PDFHigh-fidelity computational fluid dynamics modeling to simulate perfusion through a bone-mimicking scaffold.
Comput Biol Med
December 2024
University of Colorado Boulder, Paul M. Rady Department of Mechanical Engineering, Boulder, CO, USA; Biofrontiers Institute, University of Colorado, Boulder, CO, 80309, USA. Electronic address:
Breast cancer cells sense shear stresses in response to interstitial fluid flow in bone and induce specific biological responses. Computational fluid dynamics models have been instrumental in estimating these shear stresses to relate the cell mechanoresponse to exact mechanical signals, better informing experiment design. Most computational models greatly simplify the experimental and cell mechanical environments for ease of computation, but these simplifications may overlook complex cell-substrate mechanical interactions that significantly change shear stresses experienced by cells.
View Article and Find Full Text PDFEtiology, histology, and long-term outcome of bilateral testicular regression: a large Belgian series.
Hum Reprod Open
December 2023
Department of Internal Medicine and Pediatrics, Ghent University, Pediatric Endocrinology Service, Ghent University Hospital, Belgium, Ghent.
Article Synopsis
- - The study investigates the long-term effects of bilateral testicular regression (BTR) in individuals, focusing on growth and development outcomes, particularly highlighting suboptimal penile growth often related to genetic factors.
- - BTR, a rare condition with potential vascular and genetic origins, was analyzed in a cross-sectional study involving 35 participants recruited from eight pediatric endocrinology departments in Belgium over three years.
- - Key findings revealed common maternal complications during pregnancy and identified specific genetic variants in some participants, while a centralized review of gonadal tissue contributed to understanding the condition's clinical implications.
Urban land use optimization prediction considering carbon neutral development goals: a case study of Taihu Bay Core area in China.
Carbon Balance Manag
November 2024
School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou, 341000, China.
Background: Given the increasing commitment of numerous nations to achieving future carbon neutrality, urban development planning that integrating carbon storage considerations plays a crucial role in enhancing urban carbon efficiency and promoting regional sustainable development. Previous studies have indicated that optimizing land use structure and quality is essential for regional carbon storage management. Taking the core area of Taihu Bay as study area, this study innovatively combined high-precision urban 3D data to account for the whole urban carbon pools of buildings, vegetation, soils, water.
View Article and Find Full Text PDFDistributed intelligence in industrial and automotive cyber-physical systems: a review.
Front Robot AI
October 2024
Department of Electrical and Computer Engineering, University of Patras, Patras, Greece.
Cyber-physical systems (CPSs) are evolving from individual systems to collectives of systems that collaborate to achieve highly complex goals, realizing a cyber-physical system of systems (CPSoSs) approach. They are heterogeneous systems comprising various autonomous CPSs, each with unique performance capabilities, priorities, and pursued goals. In practice, there are significant challenges in the applicability and usability of CPSoSs that need to be addressed.
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