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Retinal Vasculitis in a Patient with Hansen's Disease.
Retin Cases Brief Rep
March 2024
Beth Israel Lahey Health- Lahey Clinic, Burlington Massachusetts 01805, USA.
Purpose: Hansen's disease is endemic in over 140 countries worldwide and a potentially blinding condition. We describe a case of retinal vasculitis in a patient with Hansen's disease with concomitant positive antiphospholipid antibody serology, a potentially under-reported complication in this setting.
Methods: A 37-year-old Brazilian man systemically stable on triple therapy (clofazimine, rifampin, dapsone) for Hansen's disease presented for a comprehensive ophthalmic evaluation.
Grade III Severe QT Prolongation in an Indian Male on All-Oral Longer Regimen for Multidrug-Resistant Pulmonary Tuberculosis: World's First Case.
Cureus
November 2022
Medicine, Shri Madan Lal Khurana Chest Clinic, Moti Nagar, New Delhi, IND.
Antitubercular drugs are associated with several adverse drug reactions (ADRs). Some of these ADRs are life-threatening and require immediate attention and hospital admission. With the development of new regimens and inclusions of newer drugs such as bedaquiline, pretomanid, and delamanid, it is imperative to have an eye for the side effects.
View Article and Find Full Text PDF[Suna no utsuwa (Castle of Sand): A Film Concerning Hansen's Disease].
Brain Nerve
December 2022
Department of Neurology, Tokyo Metropolitan Neurological Hospital.
Hansen's disease (also known as leprosy) is a chronic infection that is caused by Mycobacterium leprae. It predominantly affects the peripheral nerves, skin, eyes, and nasal mucosa, Following the development of effective treatment with diaphenylsulfone followed by rifampicin, and clofazimine since 1940s, Hansen's disease has been eradicated in Japan. However, the longstanding stigma surrounding this disease, exacerbated partly by forced isolation and other regulations introduced in 1930s, has delayed the abrogation of these regulations.
View Article and Find Full Text PDFMycobacterium chimaera chorioretinitis preceding central nervous system lesions: a case report and review of the literature.
BMC Ophthalmol
July 2022
Department of Ophthalmology, University of Kansas School of Medicine, 7400 State Line Rd, Prairie Village, Kansas, KS, 66208, USA.
Background: Mycobacterium chimaera ocular infection is a rare disease that is linked to bypass devices used during cardiothoracic surgeries. Reported cases in the literature of ocular involvement preceding CNS involvement are based on clinical exam with no neuroimaging. Here we present a case of M.
View Article and Find Full Text PDFComplicated case of conjunctivitis in Sjögren's syndrome.
Am J Ophthalmol Case Rep
September 2020
Gavin Herbert Eye Institute, University of California, Irvine, 92697, United States.
Purpose: To report a case of conjunctivitis due to Mycobacterium abscessus in the setting of keratoconjunctivitis sicca due to Sjögren's syndrome in the absence of other known risk factors such as surgery, trauma or immunosuppressive therapy.
Observations: A 61-year-old woman with a history of keratoconjunctivitis sicca secondary to Sjögren's syndrome presented with dryness, irritation, redness, and discharge in her left eye for 2 months. She was diagnosed with chronic conjunctivitis and began a regimen of moxifloxacin and an ocular ointment of dexamethasone, neomycin, and polymyxin with no improvement of symptoms.
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